| Entry |
|
|---|
| Name |
Nialamide (INN);
Niamid (TN) |
|---|
| Formula |
C16H18N4O2
|
|---|
| Exact mass |
298.1430
|
|---|
| Mol weight |
298.34
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidepressant, Monoamine oxidase (MAO) inhibitor |
|---|
| Target |
|
|---|
| Pathway |
| hsa00260 | Glycine, serine and threonine metabolism |
| hsa00330 | Arginine and proline metabolism |
| hsa00982 | Drug metabolism - cytochrome P450 |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AF Monoamine oxidase inhibitors, non-selective
N06AF02 Nialamide
D07337 Nialamide (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
D07337 Nialamide
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Amine oxidases
MAO
D07337 Nialamide (INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 C8x C 15.1900 -19.6700
2 N5x N 15.1900 -21.0700
3 C8x C 16.4024 -21.7700
4 C8x C 17.6149 -21.0700
5 C8y C 17.6149 -19.6700
6 C8x C 16.4024 -18.9700
7 C5a C 18.8524 -18.9700
8 N1b N 20.0649 -19.6700
9 N1b N 21.2773 -18.9700
10 C1b C 22.4897 -19.6700
11 C1b C 23.7022 -18.9700
12 C5a C 24.9146 -19.6700
13 N1b N 26.1270 -18.9700
14 C1b C 27.3395 -19.6700
15 C8y C 28.5519 -18.9700
16 C8x C 29.7704 -19.6735
17 C8x C 30.9828 -18.9735
18 C8x C 30.9829 -17.5735
19 C8x C 29.7644 -16.8700
20 C8x C 28.5519 -17.5700
21 O5a O 18.8586 -17.5703
22 O5a O 24.9146 -21.0700
BOND 23
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 2
17 16 17 1
18 17 18 2
19 18 19 1
20 19 20 2
21 15 20 1
22 7 21 2
23 12 22 2
|
|---|
