| Entry |
|
|---|
| Name |
Arformoterol (INN) |
|---|
| Formula |
C19H24N2O4
|
|---|
| Exact mass |
344.1736
|
|---|
| Mol weight |
344.40
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
|
|---|
| Remark |
| Product (DG01233): | D02981<US> |
|
|---|
| Efficacy |
Antiasthmatic, Bronchodilator, beta2-Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
Long-acting beta-adrenoceptor agonist (LABA)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01233 Arformoterol
D07463 Arformoterol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB2
D07463 Arformoterol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01233 Arformoterol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 25
1 C8y C 21.2100 -17.9900
2 C8x C 19.9500 -18.6900
3 C8x C 21.2100 -16.5900
4 C1c C 22.4000 -18.6900
5 C8y C 18.7600 -17.9900
6 C8x C 19.9500 -15.8900
7 C1b C 23.5900 -17.9900
8 C8y C 18.7600 -16.5900
9 N1b N 17.5700 -18.6900
10 N1b N 24.7800 -18.6900
11 O1a O 17.5700 -15.8900
12 C4a C 16.3100 -17.9900
13 C1c C 26.0400 -17.9900
14 O4a O 15.1200 -18.6900
15 C1b C 27.2300 -18.6900
16 C8y C 28.4200 -17.9900
17 C8x C 28.4200 -16.5900
18 C8x C 29.6100 -18.6900
19 C8x C 29.6100 -15.8900
20 C8x C 30.8700 -17.9900
21 C8y C 30.8700 -16.5900
22 O2a O 32.0600 -15.8200
23 C1a C 33.2500 -16.5200
24 C1a C 26.0400 -16.5900
25 O1a O 22.4000 -20.0900
BOND 26
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 2
6 4 7 1
7 5 8 2
8 5 9 1
9 7 10 1
10 8 11 1
11 9 12 1
12 10 13 1
13 12 14 2
14 13 15 1
15 15 16 1
16 16 17 2
17 16 18 1
18 17 19 1
19 18 20 2
20 19 21 2
21 21 22 1
22 22 23 1
23 6 8 1
24 20 21 1
25 13 24 1 #Down
26 4 25 1 #Down
|
|---|
