KEGG   DRUG: DopamineHelp
Entry
D07870                      Drug                                   

Name
Dopamine (INN);
Medopa (TN)
Formula
C8H11NO2
Exact mass
153.079
Mol weight
153.1784
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01699  Catecholamine cardiotonic
 DG01592  COMT substrate
Neuropsychiatric agent
 DG01472  Dopamine agonist
  DG01467  Dopamine D1-receptor agonist
  DG01468  Dopamine D2-receptor agonist
  DG01469  Dopamine D3-receptor agonist
  DG01470  Dopamine D4-receptor agonist
  DG01471  Dopamine D5-receptor agonist
Remark
Same as: 
ATC code: 
Chemical group: 
Activity
Antihypotensive, Cardiac stimulant, cardiotonic
Comment
Precursor of Norepinephrine
Neurotransmitter
Target
dopamine D1 receptor agonist [HSA:1812] [KO:K04144];
dopamine D2 receptor agonist [HSA:1813] [KO:K04145];
dopamine D3 receptor agonist [HSA:1814] [KO:K04146];
dopamine D4 receptor agonist [HSA:1815] [KO:K04147];
dopamine D5 receptor agonist [HSA:1816] [KO:K05840]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Metabolism
Enzyme: MAOB [HSA:4129], COMT [HSA:1312]
Transporter: SLC22A2 [HSA:6582]
Interaction
Drug interaction
Structure map
Dopamine receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA04 Dopamine
      D07870  Dopamine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D1-receptor
     Dopamine
      D07870  Dopamine (INN)
    dopamine D2-receptor
     Dopamine
      D07870  Dopamine (INN)
    dopamine D3-receptor
     Dopamine
      D07870  Dopamine (INN)
    dopamine D4-receptor
     Dopamine
      D07870  Dopamine (INN)
    dopamine D5-receptor
     Dopamine
      D07870  Dopamine (INN)
Cytochrome P450 interactions [BR:br08309]
 Transporter substrates
  SLC22A2
   Dopamine
    D07870  Dopamine (INN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from tyrosine
   Isoquinoline alkaloids
    D07870  Dopamine (INN)
BRITE hierarchy
Other DBs
CAS: 
51-61-6
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        11
            1   C8y C    27.5800  -20.4400
            2   C8x C    26.3200  -19.7400
            3   C8x C    27.5800  -21.9100
            4   C1b C    28.8400  -19.7400
            5   C8y C    25.1300  -20.4400
            6   C8x C    26.3200  -22.6100
            7   C1b C    30.0300  -20.4400
            8   C8y C    25.1300  -21.9100
            9   O1a O    23.9400  -19.7400
            10  N1a N    31.2200  -19.7400
            11  O1a O    23.9400  -22.5400
BOND        11
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     5   9 1
            9     7  10 1
            10    8  11 1
            11    6   8 2

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