KEGG   DRUG: D07870Help
Entry
D07870                      Drug                                   

Name
Dopamine (INN);
Medopa (TN)
Formula
C8H11NO2
Exact mass
153.079
Mol weight
153.1784
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypotensive;
Cardiac stimulant, cardiotonic
Remark
Same as: 
ATC code: 
Comment
Precursor of Norepinephrine
Neurotransmitter
Target
dopamine D1 receptor agonist [HSA:1812] [KO:K04144];
dopamine D2 receptor agonist [HSA:1813] [KO:K04145];
dopamine D3 receptor agonist [HSA:1814] [KO:K04146];
dopamine D4 receptor agonist [HSA:1815] [KO:K04147];
dopamine D5 receptor agonist [HSA:1816] [KO:K05840]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Metabolism
Enzyme: MAOB [HSA:4129], COMT [HSA:1312]
Transporter: SLC22A2 [HSA:6582]
Interaction
Drug interaction
Structure map
Dopamine receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA04 Dopamine
      D07870  Dopamine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D1-receptor [HSA:1812] [KO:K04144]
     Dopamine [ATC:C01CA04]
      D07870  Dopamine (INN)
    dopamine D2-receptor [HSA:1813] [KO:K04145]
     Dopamine [ATC:C01CA04]
      D07870  Dopamine (INN)
    dopamine D3-receptor [HSA:1814] [KO:K04146]
     Dopamine [ATC:C01CA04]
      D07870  Dopamine (INN)
    dopamine D4-receptor [HSA:1815] [KO:K04147]
     Dopamine [ATC:C01CA04]
      D07870  Dopamine (INN)
    dopamine D5-receptor [HSA:1816] [KO:K05840]
     Dopamine [ATC:C01CA04]
      D07870  Dopamine (INN)
BRITE hierarchy
Other DBs
CAS: 
51-61-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        11
            1   C8y C    27.5800  -20.4400
            2   C8x C    26.3200  -19.7400
            3   C8x C    27.5800  -21.9100
            4   C1b C    28.8400  -19.7400
            5   C8y C    25.1300  -20.4400
            6   C8x C    26.3200  -22.6100
            7   C1b C    30.0300  -20.4400
            8   C8y C    25.1300  -21.9100
            9   O1a O    23.9400  -19.7400
            10  N1a N    31.2200  -19.7400
            11  O1a O    23.9400  -22.5400
BOND        11
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     5   9 1
            9     7  10 1
            10    8  11 1
            11    6   8 2

» Japanese version   » Back

DBGET integrated database retrieval system