| Entry |
|
|---|
| Name |
Etilefrine (INN);
Corcanfol (TN) |
|---|
| Formula |
C10H15NO2
|
|---|
| Exact mass |
181.1103
|
|---|
| Mol weight |
181.2316
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
|
|---|
| Remark |
| Product (DG00210): | D01573<JP> |
|
|---|
| Efficacy |
Antihypotensive, Cardiotonic, Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA01 Etilefrine
D07931 Etilefrine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00210 Etilefrine
D07931 Etilefrine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D07931 Etilefrine (INN)
ADRA2
D07931 Etilefrine (INN)
ADRB
D07931 Etilefrine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00210 Etilefrine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 13
1 C8y C 20.5800 -17.9200
2 C8x C 20.5800 -19.3200
3 C8x C 21.7700 -20.0200
4 C8x C 22.9600 -19.3200
5 C8y C 22.9600 -17.9200
6 C8x C 21.7700 -17.2200
7 C1c C 24.1500 -17.2200
8 C1b C 25.4100 -17.9200
9 N1b N 26.6000 -17.2200
10 C1b C 27.7900 -17.9200
11 C1a C 29.0500 -17.2200
12 O1a O 24.1500 -15.8200
13 O1a O 19.3200 -17.2200
BOND 13
1 5 7 1
2 7 8 1
3 1 2 2
4 8 9 1
5 2 3 1
6 9 10 1
7 3 4 2
8 10 11 1
9 4 5 1
10 7 12 1
11 5 6 2
12 1 13 1
13 6 1 1
|
|---|
