| Entry |
|
|---|
| Name |
Morphine (BAN);
Morfina Dosa (TN);
Substitol (TN) |
|---|
| Formula |
C17H19NO3
|
|---|
| Exact mass |
285.1365
|
|---|
| Mol weight |
285.3377
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
Papaver somniferum [TAX: 3469]
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
Metabolizing enzyme substrate
DG02924 UGT substrate
|
|---|
| Remark |
| Product (DG00810): | D00842<JP/US> D02271<JP> |
|
|---|
| Efficacy |
Analgesic (narcotic), Opioid receptor agonist |
|---|
| Comment |
Opium alkaloid
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Other map |
| map00982 | Drug metabolism - cytochrome P450 |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AA Natural opium alkaloids
N02AA01 Morphine
D08233 Morphine (BAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00810 Morphine
D08233 Morphine
Analgesic
DG01984 Opioid analgesics
DG00810 Morphine
D08233 Morphine
Metabolizing enzyme substrate
DG02924 UGT substrate
DG00810 Morphine
D08233 Morphine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D08233 Morphine (BAN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08233
Prodrugs [br08324.html]
D08233
Narcotics and psychotropics in Japan [br08308.html]
Narcotics by Control Act Article 2 Table 1 (74 substances)
D08233
Opium and Cannabis
D08233
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00810 Morphine
Analgesic
DG01984 Opioid analgesics
DG00810 Morphine
Metabolizing enzyme substrate
DG02924 UGT substrate
DG00810 Morphine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 21
1 C1z C 21.5533 -23.4873
2 C8y C 21.5533 -22.2201
3 C1y C 22.7502 -24.1914
4 C1y C 20.4268 -24.1210
5 C1x C 22.7502 -22.8537
6 C8y C 20.4268 -21.5864
7 C8y C 22.7502 -21.5864
8 C1y C 23.8062 -23.4873
9 C2x C 22.7502 -25.4587
10 O2x O 19.0891 -22.7833
11 C1y C 20.4268 -25.4587
12 C1x C 24.9327 -22.8537
13 C8y C 20.4268 -20.2487
14 C1x C 23.8062 -22.2905
15 C8x C 22.7502 -20.2487
16 N1y N 24.9327 -24.1914
17 C2x C 21.5533 -26.1627
18 O1a O 19.3003 -26.1627
19 C8x C 21.6237 -19.6151
20 O1a O 19.3003 -19.6151
21 C1a C 26.3408 -24.1914
BOND 25
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1 #Up
5 2 6 2
6 2 7 1
7 3 8 1
8 3 9 1
9 4 10 1 #Down
10 4 11 1
11 5 12 1
12 6 13 1
13 7 14 1
14 7 15 2
15 8 16 1 #Up
16 9 17 2
17 11 18 1 #Down
18 13 19 2
19 13 20 1
20 6 10 1
21 8 14 1
22 11 17 1
23 12 16 1
24 15 19 1
25 16 21 1
|
|---|
