| Entry |
|
|---|
| Name |
Spirapril (INN) |
|---|
| Formula |
C22H30N2O5S2
|
|---|
| Exact mass |
466.1596
|
|---|
| Mol weight |
466.62
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA11 Spirapril
D08529 Spirapril (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00342 Spirapril
D08529 Spirapril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00342 Spirapril
D08529 Spirapril
Target-based classification of drugs [BR:br08310]
Peptidases and inhibitors
Metallo peptidases
Family M2
ACE (CD143)
D08529 Spirapril (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00342 Spirapril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00342 Spirapril
|
|---|
| Other DBs |
|
|---|
| LinkDB |
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|---|
| KCF data |
ATOM 31
1 N1y N 27.4400 -18.6200
2 C5a C 26.2500 -19.3200
3 C1c C 25.0600 -18.6200
4 O5a O 26.2500 -20.7200
5 N1b N 23.8000 -19.3200
6 C1a C 25.0600 -17.2200
7 C1c C 22.6100 -18.6200
8 C7a C 22.6100 -17.2200
9 C1b C 21.4200 -19.3200
10 O7a O 23.8000 -16.5200
11 O6a O 21.4200 -16.5200
12 C1b C 20.1600 -18.6200
13 C1b C 23.8000 -15.1200
14 C8y C 18.9700 -19.3200
15 C1a C 22.6100 -14.4200
16 C1y C 27.4400 -17.2200
17 C1x C 28.7700 -19.0400
18 C1z C 29.6100 -17.9200
19 C1x C 28.7700 -16.8000
20 S2x S 30.4500 -19.0400
21 C1x C 31.7800 -18.6200
22 C1x C 31.7800 -17.2200
23 S2x S 30.4500 -16.8000
24 C6a C 27.4400 -15.8200
25 O6a O 28.6300 -15.1200
26 O6a O 26.2500 -15.1200
27 C8x C 17.7800 -18.6200
28 C8x C 16.5900 -19.3900
29 C8x C 16.5900 -20.7900
30 C8x C 17.7800 -21.4200
31 C8x C 18.9700 -20.7200
BOND 33
1 1 2 1
2 2 3 1
3 2 4 2
4 3 5 1
5 3 6 1 #Up
6 5 7 1
7 7 8 1 #Up
8 7 9 1
9 8 10 1
10 8 11 2
11 9 12 1
12 10 13 1
13 12 14 1
14 13 15 1
15 1 16 1
16 1 17 1
17 17 18 1
18 18 19 1
19 16 19 1
20 18 20 1
21 20 21 1
22 21 22 1
23 22 23 1
24 18 23 1
25 16 24 1 #Down
26 24 25 1
27 24 26 2
28 14 27 2
29 27 28 1
30 28 29 2
31 29 30 1
32 30 31 2
33 14 31 1
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|---|
