| Entry |
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| Name |
Tubocurarine chloride (INN);
Tubaine (TN) |
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| Formula |
C37H42N2O6. 2Cl
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| Exact mass |
680.2420
|
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| Mol weight |
681.64
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| Structure |
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| Simcomp |
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| Class |
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG01740 Curare alkaloid
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| Remark |
|
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| Efficacy |
Neuromuscular blocking agent |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07221 | Nicotinic cholinergic receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AA Curare alkaloids
M03AA02 Tubocurarine
D08655 Tubocurarine chloride (INN)
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG00767 Tubocurarine
D08655 Tubocurarine chloride
DG01740 Curare alkaloid
DG00767 Tubocurarine
D08655 Tubocurarine chloride
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN (neuronal type)
D08655 Tubocurarine chloride (INN)
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG00767 Tubocurarine
DG01740 Curare alkaloid
DG00767 Tubocurarine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 47
1 X Cl 18.3400 -14.2800 #-
2 C8y C 25.2700 -14.1400
3 C1y C 24.1500 -14.8400
4 C8y C 25.2700 -12.8100
5 C8y C 26.4600 -14.8400
6 N2y N 22.9600 -14.1400 #+
7 C1x C 24.1500 -16.1700
8 C8x C 26.4600 -12.1100
9 C1x C 24.0800 -12.1100
10 C8y C 27.6500 -14.1400
11 C1x C 22.9600 -12.8100
12 C1a C 21.8400 -13.5100
13 C8y C 22.9600 -17.2200
14 C8y C 27.6500 -12.8100
15 O1a O 28.7700 -14.8400
16 C8x C 21.8400 -16.5900
17 C8x C 22.9600 -18.5500
18 O2a O 28.7700 -12.1100
19 C8x C 20.6500 -17.2200
20 C8y C 21.9100 -19.2500
21 C1a C 29.8900 -12.8100
22 C8y C 20.6500 -18.5500
23 O1a O 19.4600 -19.2500
24 C1a C 21.8400 -14.8400
25 O2x O 26.4600 -16.1700
26 N2y N 27.8600 -21.7000 #+
27 C1y C 26.6700 -21.0000
28 C1x C 27.8600 -23.1700
29 C8y C 25.4800 -21.7000
30 C1x C 28.8400 -20.0900
31 C1x C 26.6700 -23.8000
32 C8y C 25.4800 -23.1000
33 C8x C 24.2900 -21.0700
34 C8x C 27.5800 -18.6200
35 C8x C 24.2900 -23.8000
36 C8y C 23.1000 -21.7000
37 C8y C 28.8400 -19.3200
38 C8x C 27.5800 -17.2200
39 C8y C 23.1000 -23.1000
40 O2x O 21.9100 -21.0000
41 C8x C 30.0300 -18.6200
42 C8y C 28.7700 -16.5200
43 O2a O 21.9100 -23.8000
44 C8x C 30.0300 -17.1500
45 C1a C 20.6500 -23.1700
46 C1a C 29.7500 -20.8600
47 X Cl 29.3300 -23.3800 #-
BOND 51
1 22 23 1
2 9 11 1
3 10 14 1
4 20 22 1
5 24 6 1
6 5 25 1
7 2 3 1
8 2 4 2
9 2 5 1
10 3 6 1
11 3 7 1
12 4 8 1
13 4 9 1
14 5 10 2
15 6 11 1
16 6 12 1
17 7 13 1
18 8 14 2
19 10 15 1
20 13 16 2
21 13 17 1
22 14 18 1
23 16 19 1
24 17 20 2
25 18 21 1
26 19 22 2
27 26 27 1
28 26 28 1
29 27 29 1
30 27 30 1
31 28 31 1
32 29 32 2
33 29 33 1
34 32 35 1
35 33 36 2
36 34 37 2
37 34 38 1
38 35 39 2
39 36 40 1
40 37 41 1
41 38 42 2
42 39 43 1
43 41 44 2
44 43 45 1
45 31 32 1
46 36 39 1
47 42 44 1
48 26 46 1
49 25 42 1
50 20 40 1
51 37 30 1
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