| Entry |
|
|---|
| Name |
Solithromycin (JAN/USAN) |
|---|
| Formula |
C43H65FN6O10
|
|---|
| Exact mass |
844.4746
|
|---|
| Mol weight |
845.01
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antibiotic, Protein biosynthesis inhibitor |
|---|
| Target |
50S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
J01FA Macrolides
J01FA16 Solithromycin
D09965 Solithromycin (JAN/USAN)
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Macrolide
D09965 Solithromycin (JAN/USAN)
|
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| Other DBs |
|
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| LinkDB |
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| KCF data |
ATOM 60
1 C1y C 23.9364 -17.0659
2 C5x C 22.7549 -17.7609
3 C1y C 23.9364 -15.6760
4 C1z C 22.7549 -19.0813
5 C1z C 22.7549 -15.0505
6 C7x C 21.5736 -19.7763
7 C1x C 22.7549 -13.6606
8 O7x O 20.3922 -19.0813
9 C1y C 21.5736 -13.0351
10 C1y C 20.3922 -17.7609
11 C5x C 20.3922 -13.6606
12 C1y C 20.3922 -15.0505
13 O5x O 21.5736 -17.0659
14 O6a O 21.5736 -21.0967
15 C1z C 19.2107 -17.0659
16 C1y C 19.2107 -15.6760
17 C1a C 18.8632 -18.3168
18 C1a C 19.2107 -14.3555
19 O5x O 19.2107 -12.9656
20 C1a C 21.5736 -11.6452
21 O2a O 23.3804 -13.5216
22 C1a C 24.2144 -14.4250
23 O2a O 25.6043 -15.5370
24 C1y C 26.9942 -16.0930
25 C1y C 28.2452 -15.3980
26 O2x O 27.0637 -17.4134
27 C1y C 29.4266 -16.0930
28 O1a O 28.3147 -14.0776
29 C1y C 28.2452 -18.1778
30 C1x C 29.4266 -17.4829
31 N1c N 30.6080 -15.4675
32 C1a C 28.2452 -19.4983
33 C1a C 31.7895 -16.0930
34 C1a C 30.6080 -14.0776
35 C1a C 25.1178 -17.7609
36 C1b C 19.4192 -18.6643
37 C1a C 19.4192 -19.9848
38 C1a C 23.3804 -12.2012
39 N1y N 17.3343 -15.2590
40 C7x C 16.5004 -16.3709
41 O7x O 17.3343 -17.4829
42 O6a O 15.1104 -16.3709
43 C1b C 17.3343 -13.8691
44 C1b C 16.1529 -13.1741
45 C1b C 14.9714 -13.8691
46 C1b C 13.7900 -13.1741
47 N4y N 12.6086 -13.8691
48 C8x C 11.4877 -13.0471
49 C8y C 10.3597 -13.8590
50 N5x N 10.7833 -15.1829
51 N5x N 12.1732 -15.1891
52 C8y C 9.0652 -13.4321
53 C8x C 9.0684 -12.0622
54 C8x C 7.8643 -11.3679
55 C8x C 6.6611 -12.0636
56 C8y C 6.6619 -13.4341
57 C8x C 7.8659 -14.1284
58 N1a N 5.4283 -14.1473
59 C1a C 22.7549 -20.4712
60 X F 24.1449 -19.0813
BOND 64
1 11 19 2
2 4 6 1
3 9 20 1 #Down
4 5 7 1
5 5 21 1 #Up
6 6 8 1
7 5 22 1 #Down
8 7 9 1
9 8 10 1
10 9 11 1
11 10 15 1
12 11 12 1
13 12 16 1
14 2 13 2
15 6 14 2
16 24 23 1 #Up
17 24 25 1
18 24 26 1
19 25 27 1
20 25 28 1 #Down
21 26 29 1
22 27 30 1
23 27 31 1 #Up
24 29 32 1 #Up
25 31 33 1
26 31 34 1
27 29 30 1
28 3 23 1 #Down
29 1 35 1 #Up
30 1 2 1
31 15 16 1
32 1 3 1
33 15 17 1 #Down
34 10 36 1 #Up
35 2 4 1
36 36 37 1
37 12 18 1 #Up
38 3 5 1
39 21 38 1
40 16 39 1 #Down
41 39 40 1
42 40 41 1
43 15 41 1
44 40 42 2
45 39 43 1
46 44 43 1
47 44 45 1
48 45 46 1
49 46 47 1
50 47 48 1
51 48 49 2
52 49 50 1
53 50 51 2
54 47 51 1
55 49 52 1
56 52 53 2
57 53 54 1
58 54 55 2
59 55 56 1
60 56 57 2
61 52 57 1
62 56 58 1
63 4 59 1 #Down
64 4 60 1 #Up
|
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