KEGG   DRUG: D10006Help
Entry
D10006                      Drug                                   

Name
Eplivanserin (USAN/INN)
Formula
C19H21FN2O2
Exact mass
328.1587
Mol weight
328.3806
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of insomnia
Target
5-HT2A-receptor antagonist [HSA:3356] [KO:K04157]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT2A-receptor
     Eplivanserin
      D10006  Eplivanserin (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
130579-75-8
PubChem: 
LigandBox: 
LinkDB All DBs
KCF data Show

ATOM        24
            1   C8x C    19.3200  -22.2600
            2   C8x C    19.3200  -23.6600
            3   C8x C    20.5100  -24.3600
            4   C8x C    21.7700  -23.6600
            5   C8y C    21.7700  -22.2600
            6   C8y C    20.5100  -21.5600
            7   X   F    22.9600  -21.5600
            8   C2c C    20.5100  -20.1600
            9   C2b C    19.3200  -19.4600
            10  N2b N    21.7000  -19.4600
            11  C2b C    18.1300  -20.1600
            12  C8y C    16.9400  -19.4600
            13  C8x C    16.9400  -18.0600
            14  C8x C    15.6800  -17.3600
            15  C8y C    14.4900  -18.0600
            16  C8x C    14.4900  -19.4600
            17  C8x C    15.6800  -20.1600
            18  O1a O    13.3000  -17.3600
            19  O2a O    22.8900  -20.1600
            20  C1b C    24.0800  -19.4600
            21  C1b C    25.2700  -20.1600
            22  N1c N    26.4600  -19.4600
            23  C1a C    27.6500  -20.1600
            24  C1a C    26.4600  -18.0600
BOND        25
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     6   8 1
            9     8   9 1
            10    8  10 2
            11    9  11 2
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17   16  17 2
            18   12  17 1
            19   15  18 1
            20   10  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   22  24 1

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