| Entry |
|
|---|
| Name |
Galeterone (USAN) |
|---|
| Formula |
C26H32N2O
|
|---|
| Exact mass |
388.2515
|
|---|
| Mol weight |
388.54
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01591 Androgen receptor antagonist
DG01623 Steroid-type antiandrogen
|
|---|
| Efficacy |
Antineoplastic, Androgen synthesis inhibitor |
|---|
| Comment |
Treatment of prostate cancer
|
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| Target |
|
|---|
| Pathway |
|
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| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01591 Androgen receptor antagonist
DG01623 Steroid-type antiandrogen
D10125 Galeterone
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Cytochrome P450
CYP17A1
D10125 Galeterone (USAN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 29
1 C1x C 19.6844 -23.3864
2 C1y C 19.6844 -24.7598
3 C1x C 20.8518 -25.4464
4 C2y C 22.0878 -24.7598
5 C1z C 22.0878 -23.3864
6 C1x C 20.8518 -22.6997
7 C2x C 23.2551 -25.4464
8 C1x C 24.4225 -24.7598
9 C1y C 24.4225 -23.3864
10 C1y C 23.2551 -22.6997
11 C1y C 25.6585 -22.6997
12 C1z C 25.6585 -21.3264
13 C1x C 24.4225 -20.6397
14 C1x C 23.2551 -21.3264
15 C1x C 27.9932 -22.6997
16 C2x C 27.9932 -21.3264
17 C2y C 26.8259 -20.6397
18 N4y N 26.8259 -19.2663
19 C8y C 28.1306 -17.4809
20 C8y C 28.1306 -18.8543
21 C8x C 29.2979 -19.5410
22 C8x C 30.5340 -18.8543
23 C8x C 30.5340 -17.4809
24 C8x C 29.2979 -16.7943
25 N5x N 26.8259 -17.0689
26 C8x C 26.0019 -18.1676
27 O1a O 18.4922 -25.4416
28 C1a C 22.0878 -22.0130
29 C1a C 25.6585 -19.9530
BOND 34
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 2
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 2
20 12 17 1
21 17 18 1
22 19 20 2
23 20 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 19 24 1
28 19 25 1
29 25 26 2
30 26 18 1
31 20 18 1
32 2 27 1 #Up
33 5 28 1 #Up
34 12 29 1 #Up
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