KEGG   DRUG: Tafenoquine succinate
Entry
D10670                      Drug                                   
Name
Tafenoquine succinate (USAN);
Arakoda (TN);
Krintafel (TN)
Product
KRINTAFEL (GlaxoSmithKline LLC)
Formula
C24H28F3N3O3. C4H6O4
Exact mass
581.2349
Mol weight
581.5807
Structure
Simcomp
Remark
ATC code: P01BA07
Chemical structure group: DG01834
Product (DG01834): D10490<US> D10670<US>
Efficacy
Antimalarial
  Disease
Vivax malaria [DS:H00361]
Malaria [DS:H00361]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
  P01 ANTIPROTOZOALS
   P01B ANTIMALARIALS
    P01BA Aminoquinolines
     P01BA07 Tafenoquine
      D10670  Tafenoquine succinate (USAN) <US>
USP drug classification [BR:br08302]
 Antiparasitics
  Antiprotozoals
   Tafenoquine
    D10670  Tafenoquine succinate (USAN)
Antimicrobials [BR:br08307]
 Antiparasitics
  Antmalarials
   Aminoquinoline
    D10670  Tafenoquine succinate (USAN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10670
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10670
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D10670
Other DBs
CAS: 106635-81-8
PubChem: 254741631
LinkDB
KCF data

ATOM        41
            1   C8x C    16.1000  -15.0500
            2   C8x C    16.1000  -13.5800
            3   C8y C    17.3600  -12.8800
            4   C8x C    18.5500  -13.5800
            5   C8y C    18.5500  -15.0500
            6   C8x C    17.3600  -15.7500
            7   O2a O    19.8100  -15.7500
            8   C8y C    19.8100  -17.1500
            9   C8y C    21.0000  -17.8500
            10  C8y C    21.0000  -19.2500
            11  C8y C    19.8100  -19.9500
            12  C8x C    18.5500  -19.2500
            13  C8y C    18.5500  -17.8500
            14  C8y C    22.1900  -17.1500
            15  C8x C    23.4500  -17.8500
            16  C8y C    23.4500  -19.2500
            17  N5x N    22.1900  -20.0200
            18  O2a O    24.6400  -20.0200
            19  C1a C    22.1900  -15.7500
            20  O2a O    17.3600  -17.1500
            21  N1b N    19.8100  -21.3500
            22  C1d C    17.3600  -11.4800
            23  X   F    16.1000  -11.4800
            24  X   F    18.6200  -11.4800
            25  X   F    17.3600  -10.0100
            26  C1a C    16.1700  -17.8500
            27  C1a C    25.9000  -19.3200
            28  C1c C    21.0000  -22.1200
            29  C1b C    22.1900  -21.4200
            30  C1a C    21.0000  -23.4500
            31  C1b C    23.3800  -22.1200
            32  C1b C    24.6400  -21.4200
            33  N1a N    25.8300  -22.1200
            34  C1b C    30.9400  -16.8000
            35  C1b C    32.1300  -16.1000
            36  C6a C    29.7500  -16.1000
            37  C6a C    33.3900  -16.8000
            38  O6a O    28.4900  -16.8000
            39  O6a O    29.7500  -14.7000
            40  O6a O    34.5800  -16.1000
            41  O6a O    33.3900  -18.2000
BOND        42
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15    9  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   10  17 1
            20   16  18 1
            21   14  19 1
            22   13  20 1
            23   11  21 1
            24    3  22 1
            25   22  23 1
            26   22  24 1
            27   22  25 1
            28   20  26 1
            29   18  27 1
            30   21  28 1
            31   28  29 1
            32   28  30 1
            33   29  31 1
            34   31  32 1
            35   32  33 1
            36   34  35 1
            37   34  36 1
            38   35  37 1
            39   36  38 1
            40   36  39 2
            41   37  40 1
            42   37  41 2

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