KEGG   DRUG: Aclidinium bromide and formoterol fumarate
Entry
D11857            Mixture   Drug                                   
Name
Aclidinium bromide and formoterol fumarate;
Duaklir pressair (TN)
Product
DUAKLIR PRESSAIR (AstraZeneca Pharmaceuticals LP), DUAKLIR PRESSAIR (Covis Pharma US)
Component
Aclidinium bromide [DR:D08837], Formoterol fumarate [DR:D01373]
Class
Metabolizing enzyme substrate
 DG02924  UGT substrate
Remark
ATC code: R03AL05
Product: D11857<US>
Efficacy
Bronchodilator
  Disease
Chronic obstructive pulmonary disease [DS:H01714]
Comment
Formoterol is primarily metabolized by UDP-glucuronosyltransferase (UGT).
Metabolism
Enzyme: UGT [KO:K00699]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03A ADRENERGICS, INHALANTS
    R03AL Adrenergics in combination with anticholinergics incl. triple combinations with corticosteroids
     R03AL05 Formoterol and aclidinium bromide
      D11857  Aclidinium bromide and formoterol fumarate <US>
USP drug classification [BR:br08302]
 Respiratory Tract/Pulmonary Agents
  Bronchodilator Combinations
   Aclidinium Bromide/ Formoterol Fumarate
    D11857  Aclidinium bromide and formoterol fumarate
Drug groups [BR:br08330]
 Metabolizing enzyme substrate
  DG02924  UGT substrate
   D11857  Aclidinium bromide and formoterol fumarate
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11857
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D11857
LinkDB

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