Brunner syndrome (BRNRS) is a form of X-linked non-dysmorphic mild mental retardation. It is caused by a monoamine oxidase A (MAOA) deficiency, which leads to an excess of monoamines in the brain, such as serotonin, dopamine, and epinephrine.
Category
Inherited metabolic disorder
Brite
Human diseases in ICD-11 classification [BR:br08403]
05 Endocrine, nutritional or metabolic diseases
Metabolic disorders
Inborn errors of metabolism
5C59 Inborn errors of neurotransmitter metabolism
H00548 Brunner syndrome
Pathway-based classification of diseases [BR:br08402]
Amino acid metabolism
nt06028 Dopamine and serotonin metabolism
H00548 Brunner syndrome
Cellular process
nt06544 Neuroactive ligand signaling
H00548 Brunner syndrome
