KEGG   NETWORK: N01814
Entry
N01814                      Network                                
Name
Extracellular matrix - Basal lamina
Definition
(COL1/3/5/9/11A+DCN+VCAN+ELN) == (COL6A+THBS) == (COL4A+FBLN1/2+HSPG2+NID+FN1+SDC+AGRN+BGN+FBN1/2) == Costamere
  Expanded
((1277,1278,1281,1289,1290,50509,1297,1298,1299,1301,1302)+1634+1462+2006) == ((1291,1292,1293,131873,256076)+(7057,7058,7059,7060,1311)) == ((1282,1284,1285,1286,1287,1288)+(2192,2199)+3339+(4811,22795)+2335+(6382,6383,9672,6385)+375790+633+(2200,2201)) == Costamere
Class
nt06539 Cytoskeleton in muscle cells
Type
Reference
Pathway
hsa04820  Cytoskeleton in muscle cells
Gene
1277  COL1A1; collagen type I alpha 1 chain
1278  COL1A2; collagen type I alpha 2 chain
1281  COL3A1; collagen type III alpha 1 chain
1289  COL5A1; collagen type V alpha 1 chain
1290  COL5A2; collagen type V alpha 2 chain
50509  COL5A3; collagen type V alpha 3 chain
1297  COL9A1; collagen type IX alpha 1 chain
1298  COL9A2; collagen type IX alpha 2 chain
1299  COL9A3; collagen type IX alpha 3 chain
1301  COL11A1; collagen type XI alpha 1 chain
1302  COL11A2; collagen type XI alpha 2 chain
1634  DCN; decorin
1462  VCAN; versican
2006  ELN; elastin
1291  COL6A1; collagen type VI alpha 1 chain
1292  COL6A2; collagen type VI alpha 2 chain
1293  COL6A3; collagen type VI alpha 3 chain
131873  COL6A6; collagen type VI alpha 6 chain
256076  COL6A5; collagen type VI alpha 5 chain
7057  THBS1; thrombospondin 1
7058  THBS2; thrombospondin 2
7059  THBS3; thrombospondin 3
7060  THBS4; thrombospondin 4
1311  COMP; cartilage oligomeric matrix protein
1282  COL4A1; collagen type IV alpha 1 chain
1284  COL4A2; collagen type IV alpha 2 chain
1285  COL4A3; collagen type IV alpha 3 chain
1286  COL4A4; collagen type IV alpha 4 chain
1287  COL4A5; collagen type IV alpha 5 chain
1288  COL4A6; collagen type IV alpha 6 chain
2192  FBLN1; fibulin 1
2199  FBLN2; fibulin 2
3339  HSPG2; heparan sulfate proteoglycan 2
4811  NID1; nidogen 1
22795  NID2; nidogen 2
2335  FN1; fibronectin 1
6382  SDC1; syndecan 1
6383  SDC2; syndecan 2
9672  SDC3; syndecan 3
6385  SDC4; syndecan 4
375790  AGRN; agrin
633  BGN; biglycan
2200  FBN1; fibrillin 1
2201  FBN2; fibrillin 2
Reference
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
  Authors
Goody MF, Sher RB, Henry CA
  Title
Hanging on for the ride: adhesion to the extracellular matrix mediates cellular responses in skeletal muscle morphogenesis and disease.
  Journal
Dev Biol 401:75-91 (2015)
DOI:10.1016/j.ydbio.2015.01.002
Reference
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
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