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| Entry | Name | Description | Category | Pathway | Gene |
|---|---|---|---|---|---|
| H00208 | Hyperbilirubinemia | ... are more severe by kernicterus and jaundice. Dubin-Johnson syndrome (DJS) is caused by mutations in ABCC2, a canalicular bilirubin glucuronide and xenobiotic export pump. Rotor syndrome (RS) is caused ... | Inherited metabolic disorder |
(CN1, CN2) UGT1A1 [HSA:54658] [KO:K00699] (DJS) ABCC2 [HSA:1244] [KO:K05666] (RS) SLCO1B1 [HSA:10599] [KO:K05043] (RS) SLCO1B3 [HSA:28234] [KO:K05043] |
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| H02056 | Dubin-Johnson syndrome | ... chronic conjugated hyperbilirubinemia and impaired hepatobiliary transport of non-bile salt organic anions. It is caused by mutations in ABCC2, a canalicular bilirubin glucuronide and xenobiotic export pump. | Inherited metabolic disorder | ABCC2 [HSA:1244] [KO:K05666] |
| [ KEGG | DISEASE | DRUG | MEDICUS ] |