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Entry Name Description Category Pathway Gene
H00845 Familial amyloidosis The amyloidoses are a group of diseases in which proteins that are normally soluble deposit extracellularly in tissues as insoluble fibrils. The fibrils have a characteristic beta-pleated sheet configuration ... Nervous system disease TTR [HSA:7276] [KO:K20731]
FGA [HSA:2243] [KO:K03903]
APOA1 [HSA:335] [KO:K08757]
LYZ [HSA:4069] [KO:K13915]
B2M [HSA:567] [KO:K08055]
H00930 Hypoalphalipoproteinemia ... One form is associated with abnormal cellular cholesterol efflux caused by heterozygous mutations at the ABCA1 gene. Other forms are primary hypoalphalipoproteinemia caused by mutations of APOA1 gene. Inherited metabolic disorder ABCA1 [HSA:19] [KO:K05641]
APOA1 [HSA:335] [KO:K08757]
H02505 Atherosclerosis Atherosclerosis is a chronic inflammatory disease marked by a narrowing of the arteries from lipid-rich plaques present within the walls of arterial blood vessels. It represents the root cause of the majority ... Cardiovascular disease hsa05417 Lipid and atherosclerosis LDLR [HSA:3949] [KO:K12473]
APOB [HSA:338] [KO:K14462]
PCSK9 [HSA:255738] [KO:K13050]
LDLRAP1 [HSA:26119] [KO:K12474]
ABCG5 [HSA:64240] [KO:K05683]
ABCG8 [HSA:64241] [KO:K05684]
LCAT [HSA:3931] [KO:K00650]
ABCA1 [HSA:19] [KO:K05641]
APOA1 [HSA:335] [KO:K08757]
MEF2A [HSA:4205] [KO:K09260]
LRP6 [HSA:4040] [KO:K03068]
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