Search Result |
Top |
| Entry | Name | Description | Category | Pathway | Gene |
|---|---|---|---|---|---|
| H00056 |
Alzheimer disease Dementia due to Alzheimer disease |
... include: amyloid precursor protein (APP), presenilin 1 (PS1), presenilin 2 (PS2), and apolipoprotein E (ApoE). All mutations associated with APP and PS proteins can lead to an increase in the production of ... | Neurodegenerative disease | hsa05010 Alzheimer disease |
(AD1) APP [HSA:351] [KO:K04520] (AD2) APOE [HSA:348] [KO:K04524] (AD3) PSEN1 [HSA:5663] [KO:K04505] (AD4) PSEN2 [HSA:5664] [KO:K04522] (AD9) ABCA7 [HSA:10347] [KO:K05645] (AD18) ADAM10 [HSA:102] [KO:K06704] |
| H00156 |
Hyperlipoproteinemia, type III Dysbetalipoproteinemia |
Hyperlipoproteinemia type III is an autosomal recessive disorder characterized by the accumulation of intermediate-density lipoprotein due to mutation of apolipoprotein E. | Inherited metabolic disorder | APOE [HSA:348] [KO:K04524] | |
| H00887 | Lipoprotein glomerulopathy | ... present with proteinuria and hypertension, microhematuria is rare, and renal function becomes impaired. Rare mutations in apolipoprotein E (apoE) gene may contribute to the pathogenesis of the disease. | Inherited metabolic disorder | APOE [HSA:348] [KO:K04524] | |
| H01168 | Sea-blue histiocyte disease | ... including the bone marrow, liver, and spleen. This disorder is classified as either primary or secondary; most cases are secondary to lipid metabolic diseases. A mutation in the APOE gene has been reported. | Inherited metabolic disorder | APOE [HSA:348] [KO:K04524] |
| [ KEGG | DISEASE | DRUG | MEDICUS ] |