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Entry Name Description Category Pathway Gene
H01612 Essential thrombocythemia
Essential thrombocytosis
Thrombocythemia
... kinase activity of JAK2, resulting in uncontrolled cellular growth in the hematopoietic compartment. Calreticulin (CALR) or myeloproliferative leukemia virus oncogene (MPL) mutations occur in approximately ... Hematologic disease (THCYT1) THPO [HSA:7066] [KO:K06854]
(THCYT1) SH2B3 [HSA:10019] [KO:K12459]
(THCYT1) CALR [HSA:811] [KO:K08057]
(THCYT2) MPL [HSA:4352] [KO:K05082]
(THCYT3) JAK2 [HSA:3717] [KO:K04447]
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