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Entry | Name | Description | Category | Pathway | Gene |
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H00007 | Hodgkin lymphoma | Hodgkin's lymphoma (HL) is one of the most frequent lymphomas in the Western world and often affects young adults. HL is subdivided into classical and nodular lymphocyte-predominant forms. About 95% of ... | Cancer |
NFKBIA [HSA:4792] [KO:K04734] NFKBIE [HSA:4794] [KO:K05872] REL (amplification) [HSA:5966] [KO:K09254] FAS [HSA:355] [KO:K04390] KLHDC8B [HSA:200942] |
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H00008 | Burkitt lymphoma | Burkitt lymphoma (BL) is a highly aggressive mature B-cell non-Hodgkin's lymphoma consisting of endemic, sporadic, and immunodeficiency-associated variants. Endemic BL (eBL) affects children and young ... | Cancer |
MYC-IgH (translocation) [HSA:4609] [KO:K04377] p53 (mutation) [HSA:7157] [KO:K04451] p16/INK4A (promoter methylation) [HSA:1029] [KO:K06621] |
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H00011 | Lymphoplasmacytic lymphoma | Lymphoplasmacytic lymphoma (LPL)/Waldenstrom's macroglobulinemia (WM) is a non-Hodgkin lymphoma (NHL) subtype. LPL/WM is a neoplasm of small B-lymphocytes, plasmacytoid lymphocytes, and plasma cells, usually ... | Cancer | Pax5-IgH (translocation) [HSA:5079] [KO:K09383] | |
H00367 |
Infectious mononucleosis Epstein-Barr virus (EBV) infection |
... establishes a life-long asymptomatic infection in B cells and can contribute to oncogenesis including Burkitt's lymphoma, nasopharyngeal carcinoma, Hodgkin lymphoma, and post-transplant B cell lymphomas. | Viral infectious disease | hsa05169 Epstein-Barr virus infection | |
H00406 | Acquired immunodeficiency syndrome (AIDS) | ... HIV/AIDS can be ascribed to the profound immune deficiency in patients. HIV infection also increases the risk of autoimmune diseases and malignancies such as non-Hodgkin's lymphoma and Kaposi's sarcoma. | Immune system disease; Viral infectious disease | hsa05170 Human immunodeficiency virus 1 infection | |
H00752 | Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome and Rapp-Hodgkin syndrome | Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome (also known as Hay-Wells syndrome) and Rapp-Hodgkin syndrome are rare ectodermal dysplasias characterized by ankyloblepharon filiforme adnatum and ... | Congenital malformation | TP63 [HSA:8626] [KO:K10149] | |
H01464 | Mantle cell lymphoma | Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma (NHL) and it accounts for about 6% of all NHL cases. Diagnosis is based on lymph node, bone marrow, or tissue morphology of centrocytic lymphocytes ... | Cancer |
Cyclin D1 (overexpression) [HSA:595] [KO:K04503] p16/INK4a (deletion) [HSA:1029] [KO:K06621] p53 (mutation) [HSA:7157] [KO:K04451] |
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H02418 | Non-Hodgkin lymphoma | Non-Hodgkin lymphoma (NHL) is one of the most common hematologic malignancies worldwide. NHL includes malignant tumors of the lymphoid tissues variously resulting from the clonal growth of B cells, T cells ... | Cancer |
RAD54L [HSA:8438] [KO:K10875] RAD54B [HSA:25788] [KO:K10877] CASP10 [HSA:843] [KO:K04400] PRF1 [HSA:5551] [KO:K07818] |
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H02424 | Primary central nervous system lymphoma | Primary central nervous system lymphoma (PCNSL) is an extranodal non-Hodgkin lymphoma (NHL) confined to the brain, leptomeninges, eyes, or spinal cord. Most PCNSLs are diffuse large B-cell lymphoma (DLBCL; ... | Cancer |
MYD88 (mutation) [HSA:4615] [KO:K04729] CD79B (mutation) [HSA:974] [KO:K06507] CARD11 (mutation) [HSA:84433] [KO:K07367] TNFAIP3 (mutation) [HSA:7128] [KO:K11859] HLA-DRB5 (deletion) [HSA:3127] [KO:K06752] CDKN2A (deletion) [HSA:1029] [KO:K06621] |
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H02434 | Diffuse large B-cell lymphoma, not otherwise specified | ... otherwise specified (DLBCL, NOS) is the most common type of DLBCL. DLBCL accounts for 30-40% of all non-Hodgkin lymphomas (NHL), making it the most prevalent form of NHL. DLBCL can occur as primary disease or ... | Cancer |
EZH2 (mutation) [HSA:2146] [KO:K11430] CREBBP (mutation/deletion) [HSA:1387] [KO:K04498] EP300 (mutation/deletion) [HSA:2033] [KO:K04498] GNA13 (mutation) [HSA:10672] [KO:K04639] GNAI2 (mutation) [HSA:2768] [KO:K04346] TNFRSF14 (mutation) [HSA:8764] [KO:K05152] BCL6 (mutation) [HSA:604] [KO:K15618] MYC (chromosomal translocation) [HSA:4609] [KO:K04377] PTEN (deletion) [HSA:5728] [KO:K01110] BCL2 (chromosomal translocation / mutation) [HSA:596] [KO:K02161] CARD11 (mutation) [HSA:84433] [KO:K07367] CD79A (mutation) [HSA:973] [KO:K06506] CD79B (mutation) [HSA:974] [KO:K06507] TNFAIP3 (mutation/deletion) [HSA:7128] [KO:K11859] MYD88 (mutation) [HSA:4615] [KO:K04729] CDKN2A (deletion) [HSA:1029] [KO:K06621] CDKN2B (deletion) [HSA:1030] [KO:K04685] PRDM1 (mutation/deletion) [HSA:639] [KO:K24501] MLL2 (mutation) [HSA:8085] [KO:K09187] MLL3 (mutation) [HSA:58508] [KO:K09188] B2M (mutation/deletion) [HSA:567] [KO:K08055] CD58 (mutation/deletion) [HSA:965] [KO:K06492] TP53 (mutation) [HSA:7157] [KO:K04451] MEF2B (mutation) [HSA:100271849] [KO:K09261] FOXO1 (mutation) [HSA:2308] [KO:K07201] |
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