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| Entry | Name | Description | Category | Pathway | Gene |
|---|---|---|---|---|---|
| H00001 |
B-cell acute lymphoblastic leukemia B-cell acute lymphocytic leukemia |
... chromosome resulting in expression of the BCR-ABL1 fusion; and rearrangements of MLL (also known as KMT2A) at 11q23 to a diverse array of fusion partners. If none of these specific genetic abnormalities ... | Cancer |
BCR-ABL (translocation) [HSA:25] [KO:K06619] MLL-AF4 (translocation) [HSA:4297 4299] [KO:K09186 K15184] E2A-PBX1 (translocation) [HSA:6929 5087] [KO:K09063 K09355] TEL-AML1 (translocation) [HSA:861] [KO:K08367] c-MYC (rearrangement) [HSA:4609] [KO:K04377] CRLF2 (rearrangement) [HSA:64109] [KO:K05078] PAX5 (rearrangement) [HSA:5079] [KO:K09383] |
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| H01879 | Wiedemann-Steiner syndrome | ... syndrome [DS:H00631], WDSTS is another heterogeneous disease. WDSTS is caused by heterozygous mutations in KMT2A, also known as MLL. KMT2A encodes a histone methyltransferase that plays an important role in early ... | Congenital malformation | KMT2A [HSA:4297] [KO:K09186] |
| [ KEGG | DISEASE | DRUG | MEDICUS ] |