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Entry | Name | Description | Category | Pathway | Gene |
---|---|---|---|---|---|
H00964 | Poor metabolism of thiopurines | ... the metabolism of thiopurine drugs including azathioprine, mercaptopurine, and thioguanine. Recent studies identified germline NUDT15 variation as another critical determinant of thiopurine intolerance. | Inherited metabolic disorder |
(THPM1) TPMT [HSA:7172] [KO:K00569] (THPM2) NUDT15 [HSA:55270] [KO:K03574] |
[ KEGG | DISEASE | DRUG | MEDICUS ] |