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Entry Name Description Category Pathway Gene
H00964 Poor metabolism of thiopurines ... the metabolism of thiopurine drugs including azathioprine, mercaptopurine, and thioguanine. Recent studies identified germline NUDT15 variation as another critical determinant of thiopurine intolerance. Inherited metabolic disorder (THPM1) TPMT [HSA:7172] [KO:K00569]
(THPM2) NUDT15 [HSA:55270] [KO:K03574]
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