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Thumbnail Image |
Name |
Description |
Object |
Legend |
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mmu05412
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Arrhythmogenic right ventricular cardiomyopathy |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may... |
C00076 (Calcium cation) C00076 (Calcium cation) C00076 (Calcium cation) C00076 (Calcium cation) C013... |
ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY DHPR RyR2 SERCA2a NCX Sarcoplasmic reticulum (SR)... |
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mmu00534
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Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
Heparan sulfate (HS) and heparin (Hep) are glycosaminoglycans with repeating disaccharide units that... |
G00164 G00163 G00162 G00157 C00054 (Adenosine 3',5'-bisphosphate) G00156 G00155 G00154 C02189 ([Prot... |
...,2 EXTL1,3 XYLT1,2 B4GALT7 B3GALT6 B3GAT3 Disaccharide repeating region Linkage region tetrasacchari... |
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mmu05225
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Hepatocellular carcinoma |
Hepatocellular carcinoma (HCC) is a major type of primary liver cancer and one of the rare human neo... |
...8176 (Nras) 109880 (Braf), 110157 (Raf1), 11836 (Araf) 26395 (Map2k1), 26396 (Map2k2) 26413 (Mapk1),... |
HEPATOCELLULAR CARCINOMA EGFR Ras Raf MEK ERK1/2 Shc Grb2 SOS mTOR S6K IGF-II IGF1R PI3K-Akt signal... |
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mmu00520
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Amino sugar and nucleotide sugar metabolism |
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...D-mannosaminouronate) C04631 (UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine) C01050 (UDP-N-acetylmur... |
....5.1.56 5.1.3.9 2.7.1.192 4.2.1.126 Lipopolysaccharide biosynthesis 1.1.1.136 5.1.3.- Fructose and m... |
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mmu04130
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SNARE interactions in vesicular transport |
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224630 (Bnip1) 67023 (Use1) 71116 (Stx18) 67727 (Stx17) 12068 (Bet1), 54399 (Bet1l) 56418 (Ykt6) 533... |
...7 VAMP4 VAMP5 SNAP23 Syp7 SNAP23 Stx1-4 Stx1-4 SNARE INTERACTIONS IN VESICULAR TRANSPORT TGN (tr... |
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mmu05414
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Dilated cardiomyopathy |
Dilated cardiomyopathy (DCM) is a heart muscle disease characterised by dilation and impaired contra... |
C00076 (Calcium cation) C00076 (Calcium cation) C00076 (Calcium cation) C00076 (Calcium cation) C013... |
DILATED CARDIOMYOPATHY DHPR RyR SERCA2a NCX Sarcoplasmic reticulum (SR) T-tubule Cardiac muscle con... |
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mmu04261
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Adrenergic signaling in cardiomyocytes |
Cardiac myocytes express at least six subtypes of adrenergic receptor (AR) which include three subty... |
C00076 (Calcium cation) C00076 (Calcium cation) C00076 (Calcium cation) C01330 (Sodium cation) C0133... |
ADRENERGIC SIGNALING IN CARDIOMYOCYTES T-tubule Sarcoplasmic Reticulum (SR) DHPR RyR2 NCX NCX SER... |
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mmu05416
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Viral myocarditis |
Myocarditis is a cardiac disease associated with inflammation and injury of the myocardium. It resul... |
13138 (Dag1) 13138 (Dag1) 16772 (Lama1), 16773 (Lama2) 13405 (Dmd) 13690 (Eif4g2), 208643 (Eif4g1), ... |
VIRAL MYOCARDITIS Cardiac muscle contraction α-DAG β-DAG Laminin ECM-receptor interaction Extracell... |
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mmu05208
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Chemical carcinogenesis - reactive oxygen species |
...initiation, promotion and progression. Chemical carcinogens can alter any of these processes to indu... |
...ium) C06268 (Chromium) C06268 (Chromium) C06269 (Arsenic) C06269 (Arsenic) C07295 (Methanearsonous a... |
CHEMICAL CARCINOGENESIS - REACTIVE OXYGEN SPECIES CYP1A2 4-Aminobiphenyl N-Hydroxy-4-aminobiphe... |
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mmu05410
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Hypertrophic cardiomyopathy |
Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant patter... |
C00002 (ATP) C00076 (Calcium cation) C00076 (Calcium cation) C00076 (Calcium cation) C00076 (Calcium... |
HYPERTROPHIC CARDIOMYOPATHY DHPR RyR SERCA2a NCX Sarcoplasmic reticulum (SR) T-tubule Cardiac muscl... |
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mmu05211
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Renal cell carcinoma |
... ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem t... |
C00007 (Oxygen) C00149 ((S)-Malate) C00122 (Fumarate) C00007 (Oxygen) 19247 (Ptpn11) 21803 (Tgfb1), ... |
...2 Rbx1 ElonginB ElonginC VHL HPH HIF-α Malate Fumarate CUL2 Rbx1 ElonginB ElonginC TGF-β TGF-α PDGF-... |
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mmu03320
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PPAR signaling pathway |
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated... |
...0 (Fabp1), 16204 (Fabp6), 16592 (Fabp5) 19013 (Ppara) 20181 (Rxra), 20182 (Rxrb), 20183 (Rxrg) 19015... |
...AID AQP7 GyK PEPCK Perilipin FATCD36 FATP FABP PPARα RXR PPARβ/δ RXR PPARγ RXR SCP-X Thiolase B MCAD... |
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mmu05415
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Diabetic cardiomyopathy |
Diabetic cardiomyopathy has been defined as left ventricular dysfunction that occurs among patients ... |
...ydrogen peroxide) C21011 ([Protein]-N(epsilon)-(carboxymethyl)lysine), C21012 ([Protein]-N(epsilon)-... |
... LCFA-CoA DAG PKCα/δ FAT/CD36 Cer PP2A DIABETIC CARDIOMYOPATHY PKCβ Glucose Glucose UDP-GlcNAc Glc-6... |
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mmu04913
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Ovarian steroidogenesis |
The ovarian steroids, 17-beta estradiol (E2) and progesterone (P4), are critical for normal uterine ... |
...5'-Cyclic AMP) C00575 (3',5'-Cyclic AMP) C02249 (Arachidonyl-CoA) C00219 (Arachidonate) C05356 (5(S)... |
OVARIAN STEROIDOGENESIS Steroid hormone biosynthesis Ovary (theca interstitial cell) Ovary (granulo... |
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mmu04973
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Carbohydrate digestion and absorption |
Dietary carbohydrate in humans and omnivorous animals is a major nutrient. The carbohydrates that we... |
... C01835 (Maltotriose) C00208 (Maltose) C00369 (Starch) C00031 (D-Glucose) C00076 (Calcium cation) C0... |
CARBOHYDRATE DIGESTION AND ABSORPTION Blood Lumen Salivary secretion Small intestinal epithelial ... |
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mmu04613
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Neutrophil extracellular trap formation |
...action is the formation of neutrophil extracellular traps (NETs), the extracellular structures compo... |
...a-D-Glucan) C00464 (Mannan) C00338 (Lipopolysaccharide) 14131 (Fcgr3) 14129 (Fcgr1) 20779 (Src) 2096... |
...m signaling pathway NEUTROPHIL EXTRACELLULAR TRAP FORMATION CASP1 GSDMD TLR4 CASP11 Bacteri... |
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mmu05418
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Fluid shear stress and atherosclerosis |
Shear stress represents the frictional force that the flow of blood exerts at the endothelial surfac... |
...c oxide) C00272 (Tetrahydrobiopterin) C00925 (Heparan sulfate), C00607 (Chondroitin sulfate), C00518... |
FLUID SHEAR STRESS AND ATHEROSCLEROSIS ONOO MAPK signaling pathway p38 VCAM-1 ICAM-1 AP-1 Akt P... |
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mmu05144
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Malaria |
Plasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasi... |
C00533 (Nitric oxide) C00634 (Chondroitin 4-sulfate) G10505 (Hyaluronic acid) G00054 (Type II A anti... |
...ous tissue Liver Circulation Kupffer cell Vascular endothelial cell PfEMP1 SPECT Malaria sporozoite... |
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mmu01200
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Carbon metabolism |
Carbon metabolism is the most basic aspect of life. This map presents an overall view of central car... |
...phate) C00231 (D-Xylulose 5-phosphate) C06019 (D-arabino-Hex-3-ulose 6-phosphate) C00022 (Pyruvate) ... |
HCO HCHO HCHO HCO HCO AcCoA CARBON METABOLISM Fructose-6P Ribulose-1,5P Glycerate-3P THF Glucose Gl... |
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mmu01210
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2-Oxocarboxylic acid metabolism |
2-Oxocarboxylic acids, also called 2-oxo acids and alpha-keto acids, are the most elementary set of ... |
...ucoiberverin) C00036 (Oxaloacetate) C00049 (L-Aspartate) C03283 (L-2,4-Diaminobutanoate) C00026 (2-O... |
...3-Methylthiopropyl glucosinolate Oxaloacetate Aspartate 2,4-Diaminobutanoate 2-Oxoglutarate 2-Oxoadi... |