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Thumbnail Image |
Name |
Description |
Object |
Legend |
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hsa00982
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Drug metabolism - cytochrome P450 |
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...), 2328 (FMO3), 2329 (FMO4), 2330 (FMO5) 1576 (CYP3A4) 1576 (CYP3A4) 1576 (CYP3A4) 1576 (CYP3A4) 107... |
...Hydroxytamoxifen (active) conjugates 1.14.13.8 CYP3A4 CYP3A4 CYP3A4 CYP3A4 CYP2D6 N-Desmethyltamoxif... |
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hsa05204
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Chemical carcinogenesis - DNA adducts |
It has been estimated that exposure to environmental chemical carcinogens may contribute significant... |
...302 (Methyldiazonium ion) 1544 (CYP1A2), 1576 (CYP3A4) 1543 (CYP1A1), 1545 (CYP1B1) 1543 (CYP1A1), 1... |
...OGENESIS - DNA ADDUCTS AFB1-exo-8,9-epoxide CYP3A4 CYP1 CYP1 CYP1/2/3 B[a]P-7,8-dihydrodiol-9,10-... |
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hsa00980
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Metabolism of xenobiotics by cytochrome P450 |
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... 9446 (GSTO1) 1544 (CYP1A2) 2052 (EPHX1) 1576 (CYP3A4), 1577 (CYP3A5) 1544 (CYP1A2) 1553 (CYP2A13) 2... |
...3A CYP2A6 CYP2A13 CYP2A13 CYP2D6 CYP2E1 CYP2A6 CYP3A4 CYP2A13 CYP2A13 CYP2A13 CYP2C9 CYP3A4 CYP1B1 C... |
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hsa01100
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Metabolic pathways |
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...(CYP2C8), 1559 (CYP2C9), 1562 (CYP2C18), 1576 (CYP3A4), 1577 (CYP3A5), 1592 (CYP26A1), 29785 (CYP2S1... |
Monoterpenoid biosynthesis One carbon pool by folate Flavonoid biosynthesis Starch and sucrose metab... |
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hsa00830
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Retinol metabolism |
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...861540 (CYP3A7-CYP3A51P), 1551 (CYP3A7), 1576 (CYP3A4), 1577 (CYP3A5) 1543 (CYP1A1), 1544 (CYP1A2) 1... |
Iodopsin RETINOL METABOLISM all-trans-Retinol (Vitamine A) ADH all-trans-Retinal 1.13.11.63 β... |
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hsa00591
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Linoleic acid metabolism |
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...559 (CYP2C9) 1573 (CYP2J2) 1571 (CYP2E1) 1576 (CYP3A4) 1557 (CYP2C19), 1558 (CYP2C8), 1559 (CYP2C9) ... |
...anoate THF-diols 1.13.11.58 CYP2C CYP2J CYP2E1 CYP3A4 CYP2C CYP2J CYP2E1 CYP3A4 (5S,8R)-DiHODE 5.4.4... |
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hsa00140
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Steroid hormone biosynthesis |
Steroid hormones derived from cholesterol are a class of biologically active compounds in vertebrate... |
... (CYP19A1) 1588 (CYP19A1) 1571 (CYP2E1), 1576 (CYP3A4) 1576 (CYP3A4) 3283 (HSD3B1), 3284 (HSD3B2) 51... |
1.1.1.62 STEROID HORMONE BIOSYNTHESIS 17α-Hydroxy-pregnenolone 21-Hydroxy-pregnenolone 11β,17α,21-T... |
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hsa00983
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Drug metabolism - other enzymes |
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...UGT2B15), 7367 (UGT2B17), 79799 (UGT2A3) 1576 (CYP3A4) 2990 (GUSB) 1066 (CES1), 8824 (CES2) 1066 (CE... |
...e 3.5.4.5 3.1.1.1 (prodrug) (prodrug) 2.4.1.17 CYP3A4 3.2.1.31 3.1.1.1 Irinotecan APC NPC SN-38 SN-3... |
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hsa04976
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Bile secretion |
Bile is a vital secretion, essential for digestion and absorption of fats and fat-soluble vitamins i... |
...431 (NR0B2) 6555 (SLC10A2) 6522 (SLC4A2) 1576 (CYP3A4) 10720 (UGT2B11), 10941 (UGT2A1), 54490 (UGT2B... |
...es Portal vemous circulation Faecal output AE2 CYP3A4 UGT2B4 SULT2A1 BACS BAT Conjugation and detoxi... |
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hsa05207
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Chemical carcinogenesis - receptor activation |
Carcinogenesis is a multistage process that consists of initiation, promotion, and progression stage... |
... (UGT2B17), 79799 (UGT2A3) 1555 (CYP2B6) 1576 (CYP3A4) 9970 (NR1I3) 1545 (CYP1B1) 10728 (PTGES3) 332... |
CHEMICAL CARCINOGENESIS - RECEPTOR ACTIVATION EGFR DNA Ras Raf MEK ERK1/2 DNA PKA pCREB MAPK sig... |