| Entry |
Thumbnail Image |
Name |
Description |
Object |
Legend |
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hsa04066
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HIF-1 signaling pathway |
Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of... |
...579 (PRKCB), 5582 (PRKCG) 6513 (SLC2A1) 160287 (LDHAL6A), 3939 (LDHA), 3945 (LDHB), 3948 (LDHC), 924... |
...y NOX PLCĪ³ PKC DAG ROS ntermittent hypoxia Glut LDHA PDK-1 Glucose Pyruvate Lactate LDHA Citrate cyc... |
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hsa05230
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Central carbon metabolism in cancer |
Malignant transformation of cells requires specific adaptations of cellular metabolism to support gr... |
...HB) 23410 (SIRT3) 5315 (PKM) 5315 (PKM) 160287 (LDHAL6A), 3939 (LDHA), 3945 (LDHB), 3948 (LDHC), 924... |
...Glycolysis / glucogenesis ROS ROS SIRT3 PKM PKM LDHA PDK1 RTKs RAS RAF MEK ERK EGFR HER2 MET PI3K AK... |
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hsa01100
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Metabolic pathways |
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... 2806 (GOT2) 10993 (SDS), 113675 (SDSL) 160287 (LDHAL6A), 3939 (LDHA), 3945 (LDHB), 3948 (LDHC), 924... |
Monoterpenoid biosynthesis One carbon pool by folate Flavonoid biosynthesis Starch and sucrose metab... |
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hsa00010
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Glycolysis / Gluconeogenesis |
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (e... |
..., 5161 (PDHA2), 5162 (PDHB) 1737 (DLAT) 160287 (LDHAL6A), 3939 (LDHA), 3945 (LDHB), 3948 (LDHC), 924... |
4.1.2.13 1.2.1.3 6.2.1.13 1.2.1.5 Acetate Pentose phosphate pathway Starch and sucrose metabolism 4.... |
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hsa00270
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Cysteine and methionine metabolism |
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine throu... |
...7362 (GOT1L1), 2805 (GOT1), 2806 (GOT2) 160287 (LDHAL6A), 3939 (LDHA), 3945 (LDHB), 3948 (LDHC), 924... |
Glycolysis 2.5.1.- Ethylene 1-Aminocyclopropane-1-carboxylate 1.14.17.4 4.4.1.14 2.6.1.117 3-Methyl... |
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hsa00620
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Pyruvate metabolism |
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...3), 4199 (ME1) 4190 (MDH1), 4191 (MDH2) 160287 (LDHAL6A), 3939 (LDHA), 3945 (LDHB), 3948 (LDHC), 924... |
PYRUVATE METABOLISM Nicotinate and nicotinamide metabolism 1.2.4.1 Citrate cycle Glycine, serine an... |
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hsa00640
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Propanoate metabolism |
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...32 (ACSS1) 55902 (ACSS2), 84532 (ACSS1) 160287 (LDHAL6A), 3939 (LDHA), 3945 (LDHB), 3948 (LDHC), 924... |
PROPANOATE METABOLISM 1.2.1.18 2.1.3.1 6.4.1.2 4.1.1.9 1.2.1.75 2.6.1.18 2.6.1.19 1.1.1.59 4.2.1.27... |
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hsa04922
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Glucagon signaling pathway |
Glucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical ... |
...708 (ITPR1), 3709 (ITPR2), 3710 (ITPR3) 160287 (LDHAL6A), 3939 (LDHA), 3945 (LDHB), 3948 (LDHC), 924... |
GLUCAGON SIGNALING PATHWAY GLUT1/2 Glucose G6P Pyruvate Glucose Citrate cycle (TCA cycle) Citrate ... |