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Name |
Description |
Object |
Legend |
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hsa04976
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Bile secretion |
Bile is a vital secretion, essential for digestion and absorption of fats and fat-soluble vitamins i... |
...cristine (INN)) 366 (AQP9) 6548 (SLC9A1) 6522 (SLC4A2) 23439 (ATP1B4), 476 (ATP1A1), 477 (ATP1A2), 4... |
AQP9 BILE SECRETION Tight junction Hepatocyte NHE1 HCO Cholangiocyte AE2 ATP CFTR HCO cAMP NBC1 2HC... |
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hsa05322
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Systemic lupus erythematosus |
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by the productio... |
...407 (IGH) 1991 (ELANE) 1511 (CTSG) 727 (C5) 720 (C4A), 721 (C4B) 718 (C3) 717 (C2) 716 (C1S) 712 (C1... |
BCR FcγR FcγR IgG IgG IgG IgG Elastase Cathepsin C1s C1q C1r MAC TNF-α IFN-γ IL-10 C1q C1q CD80/86 C... |
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hsa04972
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Pancreatic secretion |
The pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two p... |
...1) 1080 (CFTR) 6344 (SCTR) 6548 (SLC9A1) 6522 (SLC4A2) 1179 (CLCA1), 22802 (CLCA4), 9635 (CLCA2) 760... |
PANCREATIC SECRETION Interstitium Lumen Tight junction Apical membrane Basolateral membrane Pancrea... |
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hsa04610
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Complement and coagulation cascades |
The complement system is a proteolytic cascade in blood plasma and a mediator of innate immunity, a ... |
...ROCR) 3075 (CFH) 718 (C3) 718 (C3) 718 (C3) 720 (C4A), 721 (C4B) 717 (C2) 4153 (MBL2) 10747 (MASP2),... |
... pathway Antigen-antibody complex Carbohydrate C4a C2b Cell lysis C6/7/8/9 CD59 Clusterin Vitrone... |
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hsa05171
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Coronavirus disease - COVID-19 |
Coronavirus disease of 2019 (COVID-19) is a highly contagious respiratory infection that is caused b... |
... 5648 (MASP1) 629 (CFB) 1675 (CFD) 718 (C3) 720 (C4A), 721 (C4B) 717 (C2) 8829 (NRP1) |
...e) C3bBb3b (C5 convertase) C4b2a (C3 convertase) C4a C2b C4b2a3b (C5 convertase) TNF signaling pathw... |
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hsa04936
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Alcoholic liver disease |
Alcoholic liver disease (ALD) refers to the damages to the liver and its functions due to alcohol ov... |
...0 (RELA) 712 (C1QA), 713 (C1QB), 714 (C1QC) 720 (C4A), 721 (C4B) 717 (C2) 7189 (TRAF6) 124 (ADH1A), ... |
MyD88 TRAF3 IFN-β IFN-α TAK1 IRAK1 IL-8 TIRAP IL-1β TBK1 TRAF6 IKKε IL-6 TAB1 TAB2 IκBα TNFα IRF3 MD... |
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hsa04964
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Proximal tubule bicarbonate reclamation |
One of the major tasks of the renal proximal tubule (PT) is to secrete acid into the tubule lumen, t... |
...id) C01353 (Carbonic acid) 6550 (SLC9A3) 8671 (SLC4A4) 6550 (SLC9A3) 762 (CA4) 760 (CA2) 27165 (GLS2... |
PROXIMAL TUBULE BICARBONATE RECLAMATION Blood Urinary lumen Proximal tubular cell Tight junction ... |
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hsa04966
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Collecting duct acid secretion |
One of the important roles of the collecting duct segment of the kidney nephron is acid secretion. A... |
...P6V0D1), 9296 (ATP6V1F), 9550 (ATP6V1G1) 6521 (SLC4A1) 495 (ATP4A), 496 (ATP4B) 760 (CA2) 10723 (SLC... |
COLLECTING DUCT ACID SECRETION Blood Urinary lumen intercalated cell type A Tight junction Tight ... |
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hsa04970
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Salivary secretion |
Saliva has manifold functions in maintaining the integrity of the oral tissues, in protecting teeth ... |
...2), 483 (ATP1B3), 486 (FXYD2) 362 (AQP5) 6522 (SLC4A2) 6548 (SLC9A1) 4069 (LYZ) 4025 (LPO) 820 (CAMP... |
SALIVARY SECRETION Interstitium Acinar lumen Tight junction Apical membrane Basolateral membrane Sa... |
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hsa04971
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Gastric acid secretion |
Gastric acid is a key factor in normal upper gastrointestinal functions, including protein digestion... |
...SLC9A4), 6548 (SLC9A1) 115111 (SLC26A7), 6522 (SLC4A2) 3784 (KCNQ1), 9992 (KCNE2) 7430 (EZR) 760 (CA... |
GASTRIC ACID SECRETION Gastric gland lumen Histamine Apical membrane Basolateral membrane Gastric ... |
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hsa05133
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Pertussis |
Pertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bact... |
...QC) 722 (C4BPA), 725 (C4BPB) 710 (SERPING1) 720 (C4A), 721 (C4B) 717 (C2) 718 (C3) 727 (C5) 1432 (MA... |
PERTUSSIS FhaC FHA SphB1 CD11b Sulfated carbohydrates CD29 FimD Fim2/3 Fimbrial proteins Adhesion Pr... |
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hsa05150
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Staphylococcus aureus infection |
Staphylococcus aureus can cause multiple forms of infections ranging from superficial skin infection... |
...15 (C1R) 712 (C1QA), 713 (C1QB), 714 (C1QC) 720 (C4A), 721 (C4B) 717 (C2) 4153 (MBL2) 10747 (MASP2),... |
C1S C1R C1Q MBL MASP1/2 STAPHYLOCOCCUS AUREUS INFECTION Alternative pathway Lectin pathway Classic... |