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Name |
Description |
Object |
Legend |
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hsa04110
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Cell cycle |
...ckpoint kinase ATM phosphorylates and activates Chk2, which in turn directly phosphorylates and acti... |
1029 (CDKN2A) 51343 (FZR1) 4171 (MCM2), 4172 (MCM3), 4173 (MCM4), 4174 (MCM5), 4175 (MCM6), 4176 (MC... |
ARF Cdh1 MCM ORC APC/C APC/C SCF SCF CDK1 BubR1 PCNA Plk1 ATM/ATR Dbf4 Mad2 Bub1 Bub3 Cdc14b 14-3-3 ... |
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hsa01100
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Metabolic pathways |
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...(AOC3) 7298 (TYMS) 2645 (GCK), 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1), 83440 (ADPGK) 5281... |
Monoterpenoid biosynthesis One carbon pool by folate Flavonoid biosynthesis Starch and sucrose metab... |
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hsa01250
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Biosynthesis of nucleotide sugars |
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... (GNE) 10020 (GNE) 2645 (GCK), 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 2645 (GCK), 3098 (H... |
BIOSYNTHESIS OF NUCLEOTIDE SUGARS GlcNAc-1P UDP-ManNAc UDP-ManNAcA UDP-L-6dTalNAc UDP-L-FucNAc UD... |
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hsa00520
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Amino sugar and nucleotide sugar metabolism |
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...IT1), 27159 (CHIA) 80896 (NPL) 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 1118 (CHIT1), 27159... |
2.7.1.59 5.4.2.3 2.7.7.23 3.2.1.183 2.7.1.60 2.5.1.57 3.1.3.29 3.5.99.6 3.5.1.25 5.4.2.10 2.3.1.157 ... |
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hsa00010
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Glycolysis / Gluconeogenesis |
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (e... |
...GPI) 5236 (PGM1), 55276 (PGM2) 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 2645 (GCK) 2821 (GP... |
4.1.2.13 1.2.1.3 6.2.1.13 1.2.1.5 Acetate Pentose phosphate pathway Starch and sucrose metabolism 4.... |
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hsa00051
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Fructose and mannose metabolism |
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...KR1B10) 6652 (SORD) 3795 (KHK) 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 3098 (HK1), 3099 (H... |
2.7.1.202 Galactose metabolism 1.1.99.21 1.1.1.21 1.1.1.14 5.3.1.5 2.7.1.3 5.3.1.7 1.1.1.11 1.1.1.67... |
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hsa00500
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Starch and sucrose metabolism |
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...ose) 57733 (GBA3) 57733 (GBA3) 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 2548 (GAA), 2595 (G... |
3.6.1.- D-Glucose-6P 3.2.1.21 3.2.1.21 2.7.1.1 3.2.1.122 STARCH AND SUCROSE METABOLISM 3.2.1.26 2... |
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hsa00600
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Sphingolipid metabolism |
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...485 (ACER2), 427 (ASAH1), 56624 (ASAH2) 56848 (SPHK2), 8877 (SPHK1) 56848 (SPHK2), 8877 (SPHK1) 8879... |
YDC1 YPC1 2.7.8.3 3.1.3.- 3.1.3.- 3.1.3.- 3.5.1.23 3.5.1.23 CERS 1.14.19.17 LAG1 1.14.18.5 1.14.18.5... |
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hsa01200
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Carbon metabolism |
Carbon metabolism is the most basic aspect of life. This map presents an overall view of central car... |
...PFKM), 5214 (PFKP) 2645 (GCK), 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1), 83440 (ADPGK) 2645... |
HCO HCHO HCHO HCO HCO AcCoA CARBON METABOLISM Fructose-6P Ribulose-1,5P Glycerate-3P THF Glucose Gl... |
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hsa05230
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Central carbon metabolism in cancer |
Malignant transformation of cells requires specific adaptations of cellular metabolism to support gr... |
...R) 6513 (SLC2A1) 6514 (SLC2A2) 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 441531 (PGAM4), 522... |
CENTRAL CARBON METABOLISM IN CANCER GLUT1/2 Glucose G6P Pyruvate Glucose GCK Glutamine Glutamate... |
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hsa00052
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Galactose metabolism |
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...17 (GLA) 2717 (GLA) 2645 (GCK) 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 3938 (LCT) 2720 (GL... |
1.1.1.251 2.7.1.200 3.2.1.22 2.7.1.144 2.7.1.11 4.1.2.40 4.1.2.21 3.2.1.85 3.2.1.22 3.2.1.26 2.4.1.6... |
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hsa00524
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Neomycin, kanamycin and gentamicin biosynthesis |
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...cin B) C12211 (UDP-kanosamine) 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 2645 (GCK) |
NEOMYCIN, KANAMYCIN AND GENTAMICIN BIOSYNTHESIS D-Glucose D-Glucose-6P 2-Deoxy-scyllo-inosose 2-... |
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hsa04020
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Calcium signaling pathway |
Ca2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is dr... |
...9127 (P2RX6) 5335 (PLCG1), 5336 (PLCG2) 56848 (SPHK2), 8877 (SPHK1) 89869 (PLCZ1) 340156 (MYLK4), 46... |
Long term depression Long term potentiation Phosphatidylinositol signaling pathway Apoptosis ... |
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hsa04066
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HIF-1 signaling pathway |
Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of... |
...B), 817 (CAMK2D), 818 (CAMK2G) 3098 (HK1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 5211 (PFKL), 5213 (... |
CUL2 Rbx1 ElonginB ElonginC VEGF PHD VHL HIF-1β p300/CBP HIF-1α Glut1 HIF-1 SIGNALING PATHWAY mTOR... |
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hsa04071
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Sphingolipid signaling pathway |
Sphingomyelin (SM) and its metabolic products are now known to have second messenger functions in a ... |
...485 (ACER2), 427 (ASAH1), 56624 (ASAH2) 56848 (SPHK2), 8877 (SPHK1) 4363 (ABCC1) 1509 (CTSD) 4217 (M... |
ERK1/2 MEK1/2 Raf AKT P13K PDK1 PIP SPHINGOLIPID SIGNALING PATHWAY MAPK signaling pathway P... |
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hsa04072
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Phospholipase D signaling pathway |
Phospholipase D (PLD) is an essential enzyme responsible for the production of the lipid second mess... |
..., 8526 (DGKE), 8527 (DGKD), 9162 (DGKI) 56848 (SPHK2), 8877 (SPHK1) 5154 (PDGFA), 5155 (PDGFB), 5603... |
MAPK signaling pathway PHOSPHOLIPASE D SIGNALING PATHWAY ERK MEK Raf-1 Ras PI3K-Akt signaling pat... |
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hsa04148
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Efferocytosis |
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...777 (PTPN6) 5781 (PTPN11) 24145 (PANX1) 56848 (SPHK2), 8877 (SPHK1) 19 (ABCA1) 102 (ADAM10), 6868 (A... |
ADGRB1 MERTK DOCK1 Rac1 GULP1 ELMO Actin polymerization ITGA STAB ITGB MFGE8 Efferocyte AXL FAK CRK ... |
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hsa04370
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VEGF signaling pathway |
There is now much evidence that VEGFR-2 is the major mediator of VEGF-driven responses in endothelia... |
...) 3791 (KDR) 5335 (PLCG1), 5336 (PLCG2) 56848 (SPHK2), 8877 (SPHK1) 5743 (PTGS2) 100137049 (PLA2G4B)... |
Cdc42 DAG Calcium signaling pathway Focal adhesion MAPK signaling pathway VEGFR2 PLCγ SPK PIP PGI CO... |
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hsa04371
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Apelin signaling pathway |
Apelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally d... |
... (PRKAB1), 5565 (PRKAB2), 5571 (PRKAG1) 56848 (SPHK2), 8877 (SPHK1) 5054 (SERPINE1) 10681 (GNB5), 27... |
APELIN SIGNALING PATHWAY APJ AMPK Sphk1 PAI-1 PI3K Akt MEK1/2 ERK1/2 P70S6K PLCβ IP3 IP3R RyR mTOR... |
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hsa04666
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Fc gamma R-mediated phagocytosis |
Phagocytosis plays an essential role in host-defense mechanisms through the uptake and destruction o... |
...2) 653361 (NCF1) 273 (AMPH), 274 (BIN1) 56848 (SPHK2), 8877 (SPHK1) 5578 (PRKCA), 5579 (PRKCB), 5582... |
Macrophage Monocyte Neutrophil FcγRIIIA FcγRIIB FcγRIIA FcγRI Src Syk CD45 IgG PI3K SHIP LAT PIP PLC... |