| Entry |
Thumbnail Image |
Name |
Description |
Object |
Legend |
|
hsa05205
|
|
Proteoglycans in cancer |
Many proteoglycans (PGs) in the tumor microenvironment have been shown to be key macromolecules that... |
... 6382 (SDC1) 1277 (COL1A1), 1278 (COL1A2) 3673 (ITGA2), 3688 (ITGB1) 3685 (ITGAV), 3690 (ITGB3) 3685... |
CD44v3 Tiam1 HER2 RhoA ROCK Ankyrin Cytoskeleton activation PI3K AKT CD44 Lipid Raft IP3R CAMKII Fil... |
|
hsa04151
|
|
PI3K-Akt signaling pathway |
The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellul... |
...801 (ITGA11), 3655 (ITGA6), 3672 (ITGA1), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3676 (ITGA4), 3... |
PIP eIF4E 4EBPs eIF4B S6K1/2 Raptor mTOR GβL Rheb TSC2 TSC1 AKT PDK1 PI3K p53 signaling pathway mTOR... |
|
hsa04510
|
|
Focal adhesion |
Cell-matrix adhesions play essential roles in important biological processes including cell motility... |
...801 (ITGA11), 3655 (ITGA6), 3672 (ITGA1), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3676 (ITGA4), 3... |
ECM-receptor interaction Cytokine-cytokine receptor interaction MAPK signaling pathway ITGB ITGA Fil... |
|
hsa04512
|
|
ECM-receptor interaction |
The extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolec... |
...4) 3696 (ITGB8) 3694 (ITGB6) 3693 (ITGB5) 3674 (ITGA2B) 3690 (ITGB3) 3695 (ITGB7) 3685 (ITGAV) 22801... |
Laminin Laminin Laminin Laminin Laminin Laminin Laminin Laminin Laminin Laminin Collagen Collagen Co... |
|
hsa04611
|
|
Platelet activation |
Platelets play a key and beneficial role for primary hemostasis on the disruption of the integrity o... |
...), 5331 (PLCB3), 5332 (PLCB4) 51206 (GP6) 3673 (ITGA2), 3688 (ITGB1) 2814 (GP5) 5336 (PLCG2) 10125 (... |
PLATELET ACTIVATION cAMP DAG Calcium signaling pathway Platelet PAR1/4 P2Y1 ADP TXA2 PLCβ GP VI α2... |
|
hsa04640
|
|
Hematopoietic cell lineage |
Blood-cell development progresses from a hematopoietic stem cell (HSC), which can undergo either sel... |
...2723407 (IGH) 3655 (ITGA6), 3672 (ITGA1), 3673 (ITGA2), 3675 (ITGA3), 3676 (ITGA4), 3678 (ITGA5) 281... |
IgM CD49 CD42 CD41 CD14 CD9 CD61 IL-11R CD59 CD55 CD35 CD44 CD235a CD36 CD36 CD117 EPOR CD125 CD114 ... |
|
hsa04810
|
|
Regulation of actin cytoskeleton |
|
...801 (ITGA11), 3655 (ITGA6), 3672 (ITGA1), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3676 (ITGA4), 3... |
PIP PIP PIP Acetylcholine TMSB4 Arp2/3 PFN WAVE2 WAVE1 HSPC300 APC NWASP Asef Abi2 Nap125 PIR121 IRS... |
|
hsa04820
|
|
Cytoskeleton in muscle cells |
|
...801 (ITGA11), 3655 (ITGA6), 3672 (ITGA1), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3676 (ITGA4), 3... |
|
|
hsa05165
|
|
Human papillomavirus infection |
Human papillomavirus (HPV) is a non-enveloped, double-stranded DNA virus. HPV infect mucoal and cuta... |
...801 (ITGA11), 3655 (ITGA6), 3672 (ITGA1), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3676 (ITGA4), 3... |
PIP 4EBPs S6K1/2 mTOR Rheb TSC2 TSC1 AKT PI3K p53 signaling pathway HUMAN PAPILLOMAVIRUS INFECTION... |
|
hsa05200
|
|
Pathways in cancer |
|
... 3915 (LAMC1), 3918 (LAMC2) 3655 (ITGA6), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3685 (ITGAV) 57... |
PATHWAYS IN CANCER DCC CASP3 CASP9 CASP3 ECAD β-catenin Wnt α-catenin β-catenin ITGB Dvl ECM ITGA ... |
|
hsa05222
|
|
Small cell lung cancer |
Lung cancer is a leading cause of cancer death among men and women in industrialized countries. Smal... |
...2) 595 (CCND1) 3688 (ITGB1) 3655 (ITGA6), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3685 (ITGAV) 77... |
p53 signaling pathway CyclinE CDK2 CyclinD1 Apoptosis ECM-receptor interaction Focal adhesion ITGB I... |
|
hsa05410
|
|
Hypertrophic cardiomyopathy |
Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant patter... |
...801 (ITGA11), 3655 (ITGA6), 3672 (ITGA1), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3676 (ITGA4), 3... |
HYPERTROPHIC CARDIOMYOPATHY DHPR RyR SERCA2a NCX Sarcoplasmic reticulum (SR) T-tubule Cardiac muscl... |
|
hsa05412
|
|
Arrhythmogenic right ventricular cardiomyopathy |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may... |
...801 (ITGA11), 3655 (ITGA6), 3672 (ITGA1), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3676 (ITGA4), 3... |
ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY DHPR RyR2 SERCA2a NCX Sarcoplasmic reticulum (SR)... |
|
hsa05414
|
|
Dilated cardiomyopathy |
Dilated cardiomyopathy (DCM) is a heart muscle disease characterised by dilation and impaired contra... |
...801 (ITGA11), 3655 (ITGA6), 3672 (ITGA1), 3673 (ITGA2), 3674 (ITGA2B), 3675 (ITGA3), 3676 (ITGA4), 3... |
DILATED CARDIOMYOPATHY DHPR RyR SERCA2a NCX Sarcoplasmic reticulum (SR) T-tubule Cardiac muscle con... |
|
hsa03271
|
|
Virion - Rotavirus |
|
3673 (ITGA2) 3688 (ITGB1) |
... core VP2 inner VP6 outer VP7 spike VP4 VP5 VP8 ITGA2 ITGB1 Receptor NSP1 Nonstructural NSP2 NSP3 NS... |
|
hsa04015
|
|
Rap1 signaling pathway |
Rap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction fo... |
... 91860 (CALML4) 7094 (TLN1), 83660 (TLN2) 3674 (ITGA2B), 3690 (ITGB3) 3937 (LCP2) 2533 (FYB1) 8631 (... |
MAPK signaling pathway RAP1 SIGNALING PATHWAY ERK MEK Raf-1 Rap1 RIAM RTK RalGDS Rac RapL MEK3,6 p... |
|
hsa04145
|
|
Phagosome |
Phagocytosis is the process of taking in relatively large particles by a cell, and is a central mech... |
..., 3693 (ITGB5) 3684 (ITGAM), 3689 (ITGB2) 3673 (ITGA2), 3688 (ITGB1) 3678 (ITGA5), 3688 (ITGB1) 60 (... |
PHAGOSOME Fc gamma R-mediated phagocytosis Endocytosis Phagocytic cup pathogen Conventional p... |
|
hsa04613
|
|
Neutrophil extracellular trap formation |
Neutrophils play a central role in innate immune defense. One of the mechanisms of neutrophil action... |
...8 (C3) 727 (C5) 4790 (NFKB1), 5970 (RELA) 3674 (ITGA2B) 3690 (ITGB3) 64581 (CLEC7A) 23569 (PADI4) 23... |
Neutrophil FcγRIIA FcγRI Src Syk IgG PI3K PIP PLC DAG PKC Raf1 MEK ERK1/2 Akt NOD-like receptor sign... |
|
hsa05418
|
|
Fluid shear stress and atherosclerosis |
Shear stress represents the frictional force that the flow of blood exerts at the endothelial surfac... |
...A), 5155 (PDGFB) 1906 (EDN1) 7422 (VEGFA) 3674 (ITGA2B), 3685 (ITGAV), 3690 (ITGB3) 6714 (SRC) 5747 ... |
FLUID SHEAR STRESS AND ATHEROSCLEROSIS ONOO MAPK signaling pathway p38 VCAM-1 ICAM-1 AP-1 Akt P... |