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Name |
Description |
Object |
Legend |
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hsa04928
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Parathyroid hormone synthesis, secretion and action |
Parathyroid hormone (PTH) is a key regulator of calcium and phosphorus homeostasis. The principal re... |
...2771 (GNAI2), 2773 (GNAI3) 10893 (MMP24), 4323 (MMP14), 4324 (MMP15), 4325 (MMP16), 4326 (MMP17), 64... |
...osis c-fos αNAC αNAC JunD Bglap2 Lrp6 cbfα/runt MMP13 c-fos Npt2a 3Na 25(OH)D 1,25(OH) 1,24,25(OH) (... |
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hsa04657
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IL-17 signaling pathway |
The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial roles... |
...4586 (MUC5AC), 727897 (MUC5B) 4318 (MMP9) 4322 (MMP13) 3565 (IL4) 3567 (IL5) 3596 (IL13) 6361 (CCL17... |
...D DNA CXCL1 CCL2 CCL7 CCL20 defensin MUC5 MMP9 MMP13 IL-4 IL-5 IL-13 TARC Th17 cell differentiation... |
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hsa04926
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Relaxin signaling pathway |
Human relaxin-2 ("relaxin"), originally identified as a peptidic hormone of pregnancy, is now known ... |
...86 (COL4A4), 1287 (COL4A5), 1288 (COL4A6) 4312 (MMP1) 4313 (MMP2) 4318 (MMP9) 4322 (MMP13) 122042 (R... |
...sodilator mechanisms) TGFβ pSmad2 αSMA Collagen MMP1 MMP2 MMP9 MMP13 Anti-fibrosis RXFP2 Gβγ INSL3 G... |
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hsa05417
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Lipid and atherosclerosis |
Atherosclerosis is a chronic inflammatory disease marked by a narrowing of the arteries from lipid-r... |
... 5595 (MAPK3) 9138 (ARHGEF1) 9475 (ROCK2) 4312 (MMP1) 387 (RHOA) 10000 (AKT3), 207 (AKT1), 208 (AKT2... |
...Calcium signaling pathway Ras ERK ARHGEF1 ROCK2 MMP1 Rho PIP AKT PI3K BAD Bcl-xL Bcl-2 Fluid shear s... |
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hsa04668
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TNF signaling pathway |
Tumor necrosis factor (TNF), as a critical cytokine, can induce a wide range of intracellular signal... |
...(JUN) 3726 (JUNB) 4314 (MMP3) 4318 (MMP9) 4323 (MMP14) 1906 (EDN1) 2277 (VEGFD), 7424 (VEGFC) 64127 ... |
...ocs3 Tnfaip3 Traf1 Ifi47 Fos Jun JunB Mmp3 Mmp9 Mmp14 Edn1 Vegfc Nod2 Icam1 Sele Vcam1 Ptgs2 Leukocy... |
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hsa05206
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MicroRNAs in cancer |
MicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, ... |
...COMMD3-BMI1), 648 (BMI1) 406938 (MIR146A) 4325 (MMP16) 406991 (MIR21) 7078 (TIMP3) 8434 (RECK) 6935 ... |
...miR-34a miR-128 EGFR IRS-2 Notch Bmi-1 miR-146a MMP16 miR-21 TIMP3 RECK Colorectal cancer Glioma Pro... |
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hsa05323
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Rheumatoid arthritis |
Rheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affect... |
...(IFNG) 1437 (CSF2) 3569 (IL6) 3553 (IL1B) 4312 (MMP1), 4314 (MMP3) 1514 (CTSL) 3600 (IL15) 102723407... |
...l TGFβ LTβ B cell IL11 MCSF IFNγ GMCSF IL6 IL1β MMP1/3 CTSL IL15 Inflammation Joint destruction Auto... |
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hsa03060
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Protein export |
The protein export is the active transport of proteins from the cytoplasm to the exterior of the cel... |
...(SPCS3) 23478 (SEC11A), 90701 (SEC11C) 196294 (IMMP1L) 83943 (IMMP2L) 58477 (SRPRB) 10952 (SEC61B) 2... |
TatE Ffs YidC TatB TatC TatA SecA SecY SecE SecG SecD/F YajC SPase I SPase II SRP14 SRP72 SRP68 SRP5... |
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hsa03320
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PPAR signaling pathway |
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated... |
...57 (HMGCS1), 3158 (HMGCS2) 10580 (SORBS1) 4312 (MMP1) 2167 (FABP4) 51129 (ANGPTL4) 51 (ACOX1), 8309 ... |
Unsaturated fatty acid Unsaturated fatty acid Saturated fatty acid Eicosanoid Fibrate drug NSAID 9-c... |
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hsa04912
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GnRH signaling pathway |
Gonadotropin-releasing hormone (GnRH) secretion from the hypothalamus acts upon its receptor in the ... |
... 91860 (CALML4) 2767 (GNA11), 2776 (GNAQ) 4323 (MMP14) 2798 (GNRHR) 5337 (PLD1), 5338 (PLD2) 2778 (G... |
PKC αGSU LHβ PA, PE DAG PLCβ CDC42 cAMP CREB CaMK MKK3/6 p38MAPK MEKK BMK PLA2 IP3R CaM q/11 MT1 GnR... |
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hsa05171
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Coronavirus disease - COVID-19 |
Coronavirus disease of 2019 (COVID-19) is a highly contagious respiratory infection that is caused b... |
...F) 3592 (IL12A), 3593 (IL12B) 4314 (MMP3) 4312 (MMP1) 6347 (CCL2) 3576 (CXCL8) 6773 (STAT2) 10052923... |
ACE2 Angiotensin II Angiotensin (1-7) AT1R MAS1 CORONAVIRUS DISEASE - COVID-19 Vascular smooth mu... |
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hsa05200
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Pathways in cancer |
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... 7422 (VEGFA), 7423 (VEGFB), 7424 (VEGFC) 4312 (MMP1), 4313 (MMP2), 4318 (MMP9) 3576 (CXCL8) 595 (CC... |
PATHWAYS IN CANCER DCC CASP3 CASP9 CASP3 ECAD β-catenin Wnt α-catenin β-catenin ITGB Dvl ECM ITGA ... |
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hsa05219
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Bladder cancer |
The urothelium covers the luminal surface of almost the entire urinary tract, extending from the ren... |
3265 (HRAS) 4312 (MMP1), 4313 (MMP2), 4318 (MMP9) 1890 (TYMP) 7422 (VEGFA) 3576 (CXCL8) 7057 (THBS1)... |
Adherens junction H-Ras VEGF signaling pathway ErbB signaling pathway MMPs VEGF IL-8 TSP-1 EGFR E-ca... |