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Name |
Description |
Object |
Legend |
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hsa04260
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Cardiac muscle contraction |
Contraction of the heart is a complex process initiated by the electrical excitation of cardiac myoc... |
...(CACNA2D2), 93589 (CACNA2D4) 6262 (RYR2) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 6543 (SLC8A2), ... |
CARDIAC MUSCLE CONTRACTION T-tubule Sarcoplasmic Reticulum (SR) DHPR RyR2 NCX NCX Systole Diastole... |
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hsa04020
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Calcium signaling pathway |
Ca2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is dr... |
... 7417 (VDAC2), 7419 (VDAC3) 10105 (PPIF) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 6543 (SLC8A2), ... |
Long term depression Long term potentiation Phosphatidylinositol signaling pathway Apoptosis ... |
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hsa04261
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Adrenergic signaling in cardiomyocytes |
Cardiac myocytes express at least six subtypes of adrenergic receptor (AR) which include three subty... |
...(CACNA2D2), 93589 (CACNA2D4) 6262 (RYR2) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 6543 (SLC8A2), ... |
ADRENERGIC SIGNALING IN CARDIOMYOCYTES T-tubule Sarcoplasmic Reticulum (SR) DHPR RyR2 NCX NCX SER... |
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hsa04022
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cGMP-PKG signaling pathway |
Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO... |
...0993 (CREB3L1), 9586 (CREB5) 7408 (VASP) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 23439 (ATP1B4),... |
cGMP-PKG SIGNALING PATHWAY MLCP MLC NPR-A cGMP PKG s-GC Sarcoplasmic reticulum (SR) Kca NPR-B Myosi... |
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hsa04371
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Apelin signaling pathway |
Apelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally d... |
...), 4634 (MYL3), 4635 (MYL4) 5581 (PRKCE) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 595 (CCND1) 107... |
APELIN SIGNALING PATHWAY APJ AMPK Sphk1 PAI-1 PI3K Akt MEK1/2 ERK1/2 P70S6K PLCβ IP3 IP3R RyR mTOR... |
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hsa04740
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Olfactory transduction |
Within the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity tr... |
...156 (GRK2), 157 (GRK3) 123041 (SLC24A4), 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 3000 (GUCY2D) 1... |
OLFACTORY TRANSDUCTION cAMP Golf ACⅢ CNG CaCC Olfactory receptor neuron (ORN) Depolarization ODOR ... |
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hsa04961
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Endocrine and other factor-regulated calcium reabsorption |
Calcium (Ca2+) is essential for numerous physiological functions including intracellular signalling ... |
...5) 5745 (PTH1R) 56302 (TRPV5) 7421 (VDR) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 490 (ATP2B1), 4... |
Blood DNA Urinary lumen Nucleus Distal convoluted tubular (DCT) cell Tight junction Tight junction ... |
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hsa04974
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Protein digestion and absorption |
Protein is a dietary component essential for nutritional homeostasis in humans. Normally, ingested p... |
...6A2), 206358 (SLC36A1), 285641 (SLC36A3) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 1803 (DPP4), 42... |
PROTEIN DIGESTION AND ABSORPTION Blood Lumen Small intestinal epithelial cell Tight junction Tigh... |
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hsa04978
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Mineral absorption |
Minerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals... |
...491 (ATP2B2), 492 (ATP2B3), 493 (ATP2B4) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 7421 (VDR) 5550... |
MINERAL ABSORPTION Blood Lumen Small intestinal epithelial cell Tight junction Tight junction Tight... |
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hsa05410
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Hypertrophic cardiomyopathy |
Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant patter... |
...487 (ATP2A1), 488 (ATP2A2), 489 (ATP2A3) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 22801 (ITGA11),... |
HYPERTROPHIC CARDIOMYOPATHY DHPR RyR SERCA2a NCX Sarcoplasmic reticulum (SR) T-tubule Cardiac muscl... |
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hsa05412
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Arrhythmogenic right ventricular cardiomyopathy |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may... |
...487 (ATP2A1), 488 (ATP2A2), 489 (ATP2A3) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 1605 (DAG1) 160... |
ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY DHPR RyR2 SERCA2a NCX Sarcoplasmic reticulum (SR)... |
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hsa05414
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Dilated cardiomyopathy |
Dilated cardiomyopathy (DCM) is a heart muscle disease characterised by dilation and impaired contra... |
...487 (ATP2A1), 488 (ATP2A2), 489 (ATP2A3) 6543 (SLC8A2), 6546 (SLC8A1), 6547 (SLC8A3) 22801 (ITGA11),... |
DILATED CARDIOMYOPATHY DHPR RyR SERCA2a NCX Sarcoplasmic reticulum (SR) T-tubule Cardiac muscle con... |