KEGG   DRUG: Mannitol
Entry
D00062                      Drug                                   
Name
Mannitol (USP);
D-Mannitol (JP18);
Osmitrol (TN);
Tobrex (TN);
Bronchitol (TN)
Product
ARIDOL BRONCHIAL CHALLENGE TEST KIT (Methapharm), BRONCHITOL (Arna Pharma Pty), BRONCHITOL (Chiesi USA), MANNITOL (B. Braun Medical), MANNITOL (HF Acquisition Co LLC), MANNITOL (Henry Schein), MANNITOL (Hospira), MANNITOL (ICU Medical), OSMITROL (Baxter Healthcare Corporation)
  Generic
MANNITOL (Fresenius Kabi USA)
Formula
C6H14O6
Exact mass
182.0790
Mol weight
182.17
Structure
Simcomp
Remark
Same as: C00392
Therapeutic category: 2190
ATC code: A06AD16 B05BC01 B05CX04 R05CB16 V04CX04
Product: D00062<JP/US>
Product (mixture): D04271<JP/US>
Efficacy
Antihypertensive (intracranial, intraocular), Diagnostic aid (renal function determination), Diuretic
Comment
Osmotic diuretics
Interaction
Structure map
map07054  Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A06 DRUGS FOR CONSTIPATION
   A06A DRUGS FOR CONSTIPATION
    A06AD Osmotically acting laxatives
     A06AD16 Mannitol
      D00062  Mannitol (USP) <JP/US>
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05B I.V. SOLUTIONS
    B05BC Solutions producing osmotic diuresis
     B05BC01 Mannitol
      D00062  Mannitol (USP) <JP/US>
   B05C IRRIGATING SOLUTIONS
    B05CX Other irrigating solutions
     B05CX04 Mannitol
      D00062  Mannitol (USP) <JP/US>
 R RESPIRATORY SYSTEM
  R05 COUGH AND COLD PREPARATIONS
   R05C EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
    R05CB Mucolytics
     R05CB16 Mannitol
      D00062  Mannitol (USP) <JP/US>
 V VARIOUS
  V04 DIAGNOSTIC AGENTS
   V04C OTHER DIAGNOSTIC AGENTS
    V04CX Other diagnostic agents
     V04CX04 Mannitol
      D00062  Mannitol (USP) <JP/US>
USP drug classification [BR:br08302]
 Respiratory Tract/Pulmonary Agents
  Cystic Fibrosis Agents
   Cystic Fibrosis Agents, Other
    Mannitol
     D00062  Mannitol (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D00062  Mannitol (USP); D-Mannitol (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00062  D-Mannitol
  D00062  D-Mannitol injection
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00062
Other DBs
CAS: 69-65-8
PubChem: 7847130
ChEBI: 16899
PDB-CCD: MTL[PDBj]
LigandBox: D00062
NIKKAJI: J2.369H
LinkDB
KCF data

ATOM        12
            1   O1a O    21.5001  -19.4028
            2   C1b C    22.6912  -18.7022
            3   C1c C    23.9524  -19.4028
            4   C1c C    25.1434  -18.7022
            5   C1c C    26.3345  -19.4028
            6   C1c C    27.5957  -18.7022
            7   C1b C    28.7868  -19.4028
            8   O1a O    29.9779  -18.7022
            9   O1a O    23.9524  -20.8041
            10  O1a O    27.5957  -17.3009
            11  O1a O    25.1434  -17.3009
            12  O1a O    26.3345  -20.8041
BOND        11
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     6   7 1
            7     7   8 1
            8     3   9 1 #Down
            9     6  10 1 #Down
            10    4  11 1 #Up
            11    5  12 1 #Up

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