| Entry |
|
|---|
| Name |
Flurandrenolide (USP);
Fludroxycortide (JAN/INN);
Cordran (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C24H33FO6
|
|---|
| Exact mass |
436.2261
|
|---|
| Mol weight |
436.5136
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 2646 |
|
|---|
| Efficacy |
Anti-inflammatory, Antipruritic, Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Lipids [BR:br08002]
ST Sterol lipids
ST02 Steroids
ST0203 C21 steroids (gluco/mineralocorticoids, progestogens) and derivatives
D00328 Flurandrenolide
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AC Corticosteroids, potent (group III)
D07AC07 Fludroxycortide
D00328 Flurandrenolide (USP) <JP/US>
USP drug classification [BR:br08302]
Dermatological Agents
Dermatitis and Pruitus Agents
Glucocorticoids, Medium Potency
Flurandrenolide
D00328 Flurandrenolide (USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
26 Epidermides
264 Analgesics, anti-itchings, astringents, anti-inflammatory agents
2646 Adrenocorticotropic hormones
D00328 Flurandrenolide (USP); Fludroxycortide (JAN/INN)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00328 Flurandrenolide (USP) <JP/US>
Topical steroids potency [br08317.html]
Classification in the USA
D00328
|
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| Other DBs |
|
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| LinkDB |
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| KCF data |
ATOM 31
1 C1z C 22.9890 -17.6284
2 C1z C 21.7992 -18.2991
3 C1y C 24.1674 -18.3284
4 O2x O 24.3950 -16.9284
5 C5a C 23.0007 -16.2518
6 C1y C 21.7816 -19.6641
7 C1x C 20.6091 -17.5991
8 C1a C 21.7583 -16.8525
9 C1x C 24.1500 -19.6934
10 O2x O 25.6608 -18.3167
11 C1z C 25.7190 -16.9225
12 C1b C 21.8225 -15.5518
13 O5a O 24.2082 -15.5809
14 C1y C 20.5974 -20.3408
15 C1y C 19.4192 -18.2758
16 C1a C 25.6549 -15.7384
17 C1a C 27.0432 -16.9225
18 O1a O 21.8399 -14.1809
19 C1y C 19.4133 -19.6467
20 C1x C 20.5974 -21.7117
21 O1a O 18.2408 -17.5758
22 C1z C 18.2175 -20.3291
23 C1y C 19.3959 -22.4000
24 C2y C 18.2117 -21.7000
25 C1x C 17.0276 -19.6467
26 C1a C 18.2117 -19.0808
27 X F 19.3901 -23.7707
28 C2x C 17.0276 -22.3941
29 C1x C 15.8377 -20.3291
30 C5x C 15.8377 -21.7000
31 O5x O 14.6476 -22.3941
BOND 35
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 1 5 1 #Up
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 1
9 3 10 1 #Down
10 4 11 1
11 5 12 1
12 5 13 2
13 6 14 1
14 7 15 1
15 11 16 1
16 11 17 1
17 12 18 1
18 14 19 1
19 14 20 1
20 15 21 1 #Up
21 19 22 1
22 20 23 1
23 22 24 1
24 22 25 1
25 22 26 1 #Up
26 23 27 1 #Down
27 24 28 2
28 25 29 1
29 28 30 1
30 30 31 2
31 6 9 1
32 10 11 1
33 15 19 1
34 23 24 1
35 29 30 1
|
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