| Entry |
|
|---|
| Name |
Brofaromine (INN);
Consonar (TN) |
|---|
| Formula |
C14H16BrNO2
|
|---|
| Exact mass |
309.0364
|
|---|
| Mol weight |
310.19
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
|
|---|
| Efficacy |
Antidepressant, Monoamine oxidase A (MAO-A) inhibitor |
|---|
| Target |
|
|---|
| Pathway |
| hsa00260 | Glycine, serine and threonine metabolism |
| hsa00330 | Arginine and proline metabolism |
| hsa00982 | Drug metabolism - cytochrome P450 |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07216 | Catecholamine transferase inhibitors |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
D02560 Brofaromine
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Amine oxidases
MAOA
D02560 Brofaromine (INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 18
1 C8y C 14.2800 -14.7700
2 C8y C 14.2800 -13.3700
3 C8y C 13.0676 -12.6700
4 C8x C 11.8551 -13.3700
5 C8y C 11.8551 -14.7700
6 C8x C 13.0676 -15.4700
7 C8x C 15.6115 -15.2026
8 C8y C 16.4344 -14.0700
9 O2x O 15.6115 -12.9374
10 X Br 13.0676 -11.2702
11 O2a O 10.6240 -15.4810
12 C1a C 9.4188 -14.7853
13 C1y C 17.8500 -14.0700
14 C1x C 18.5500 -15.2824
15 C1x C 19.9500 -15.2824
16 N1x N 20.6500 -14.0700
17 C1x C 19.9500 -12.8576
18 C1x C 18.5500 -12.8576
BOND 20
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 2
9 8 9 1
10 2 9 1
11 3 10 1
12 5 11 1
13 11 12 1
14 8 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 13 18 1
|
|---|
