| Entry |
|
|---|
| Name |
Alvameline maleate (USAN) |
|---|
| Formula |
C9H15N5. C4H4O4
|
|---|
| Exact mass |
309.1437
|
|---|
| Mol weight |
309.3211
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01490 Muscarinic cholinergic receptor agonist
|
|---|
| Efficacy |
Dementia therapeutic agent, Muscarinic acetylcholine receptor agonist/antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
D02876 Alvameline maleate
DG01490 Muscarinic cholinergic receptor agonist
D02876 Alvameline maleate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM1
D02876 Alvameline maleate (USAN)
CHRM2
D02876 Alvameline maleate (USAN)
CHRM3
D02876 Alvameline maleate (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 C2b C 25.2513 -16.9630
2 C2b C 23.5507 -16.9630
3 C6a C 25.8891 -18.1677
4 C6a C 22.9129 -18.1677
5 O6a O 25.2513 -19.3015
6 O6a O 27.2355 -18.1677
7 O6a O 21.4957 -18.1677
8 O6a O 23.5507 -19.3015
9 N1y N 10.1500 -17.6400
10 C1x C 10.1500 -19.0400
11 C1x C 11.3400 -19.7400
12 C2x C 12.6000 -19.0400
13 C2y C 12.6000 -17.6400
14 C1x C 11.3400 -16.9400
15 C1a C 8.9600 -16.9400
16 C8y C 13.7900 -16.9400
17 N5x N 14.9100 -17.7800
18 N4y N 16.0300 -16.9400
19 N5x N 15.6100 -15.6100
20 N5x N 14.2100 -15.6100
21 C1b C 17.2200 -17.6400
22 C1a C 18.4100 -16.9400
BOND 22
1 1 2 2
2 1 3 1
3 2 4 1
4 3 5 1
5 3 6 2
6 4 7 1
7 4 8 2
8 9 10 1
9 10 11 1
10 11 12 1
11 12 13 2
12 13 14 1
13 9 14 1
14 9 15 1
15 13 16 1
16 16 17 2
17 17 18 1
18 18 19 1
19 19 20 2
20 16 20 1
21 18 21 1
22 21 22 1
|
|---|
