| Entry |
|
|---|
| Name |
Depelestat (USAN/INN) |
|---|
| Formula |
C282H412N74O75S6
|
|---|
| Exact mass |
6226.9024
|
|---|
| Mol weight |
6231.1295
|
|---|
| Sequence |
H-Glu Ala Cys Asn Leu Pro Ile Val Arg Gly Pro Cys Ile Ala Phe Phe
Pro Arg Trp Ala Phe Asp Ala Val Lys Gly Lys Cys Val Leu Phe Pro
Tyr Gly Gly Cys Gln Gly Asn Gly Asn Lys Phe Tyr Ser Glu Lys Glu
Cys Arg Glu Tyr Cys Gly Val Pro-OH
(Disulfide bridge: 3-53, 12-36, 28-49) |
|---|
| Type |
Peptide |
|---|
| Efficacy |
Anti-inflammatory, Elastase inhibitor |
|---|
| Comment |
Treatment of bronchopulmonary inflammatory damage, specifically Cystic Fibrosis
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Serine peptidases
ELANE
D03686 Depelestat (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
