KEGG   DRUG: Depelestat
Entry
D03686                      Drug                                   

Name
Depelestat (USAN/INN)
Formula
C282H412N74O75S6
Exact mass
6226.9024
Mol weight
6231.1295
Sequence
H-Glu Ala Cys Asn Leu Pro Ile Val Arg Gly Pro Cys Ile Ala Phe Phe
Pro Arg Trp Ala Phe Asp Ala Val Lys Gly Lys Cys Val Leu Phe Pro
Tyr Gly Gly Cys Gln Gly Asn Gly Asn Lys Phe Tyr Ser Glu Lys Glu
Cys Arg Glu Tyr Cys Gly Val Pro-OH
(Disulfide bridge: 3-53, 12-36, 28-49)
  Type
Peptide
Efficacy
Anti-inflammatory, Elastase inhibitor
Comment
Treatment of bronchopulmonary inflammatory damage, specifically Cystic Fibrosis
Target
ELANE [HSA:1991] [KO:K01327]
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Serine peptidases
    ELANE
     D03686  Depelestat (USAN/INN)
Other DBs
CAS: 506433-25-6
PubChem: 17397782
LinkDB

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