| Entry |
|
|---|
| Name |
Velaglucerase alfa (USAN);
Velaglucerase alfa (genetical recombination) (JAN);
Vpriv (TN)
|
|---|
| Product |
|
|---|
| Formula |
C2532H3854N672O711S16
|
|---|
| Exact mass |
55562.1608
|
|---|
| Mol weight |
55596.809
|
|---|
| Sequence |
ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH
TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR
VPMASCDFSI RTYTYADTPD DFQLHNFSLP EEDTKLKIPL IHRALQLAQR PVSLLASPWT
SPTWLKTNGA VNGKGSLKGQ PGDIYHQTWA RYFVKFLDAY AEHKLQFWAV TAENEPSAGL
LSGYPFQCLG FTPEHQRDFI ARDLGPTLAN STHHNVRLLM LDDQRLLLPH WAKVVLTDPE
AAKYVHGIAV HWYLDFLAPA KATLGETHRL FPNTMLFASE ACVGSKFWEQ SVRLGSWDRG
MQYSHSIITN LLYHVVGWTD WNLALNPEGG PNWVRNFVDS PIIVDITKDT FYKQPMFYHL
GHFSKFIPEG SQRVGLVASQ KNDLDAVALM HPDGSAVVVV LNRSSKDVPL TIKDPAVGFL
ETISPGYSIH TYLWRRQ (Glycosylation site: 19; 59; 146; 270; 462) |
|---|
| Type |
Peptide |
|---|
| Remark |
| Therapeutic category: | 3959 |
|
|---|
| Efficacy |
Lysosomal storage disease treatment, Enzyme replacement (glucocerebrosidase) |
|---|
| Disease |
Type 1 Gaucher disease [DS: H00126] |
|---|
| Comment |
Enzyme replacement therapy product
|
|---|
| Target |
|
|---|
| Network |
| N10017 | Replacement of deficient GBA |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16AB Enzymes
A16AB10 Velaglucerase alfa
D09029 Velaglucerase alfa (USAN) <JP/US>
USP drug classification [BR:br08302]
Genetic, Enzyme, or Protein Disorder: Replacement, Modifiers, Treatment
Velaglucerase Alfa
D09029 Velaglucerase alfa (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
395 Enzyme preparations
3959 Others
D09029 Velaglucerase alfa (USAN); Velaglucerase alfa (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Glycosidases
GBA* [HSA_VAR:2629v1]
D09029 Velaglucerase alfa (USAN) <JP/US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D09029
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D09029
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D09029
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D09029
Pharmacogenomic biomarkers [br08341.html]
Germline mutations in genetic disorder treatments
D09029
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| Other DBs |
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| LinkDB |
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