| Entry |
|
|---|
| Name |
Arbaclofen (USAN) |
|---|
| Formula |
C10H12ClNO2
|
|---|
| Exact mass |
213.0557
|
|---|
| Mol weight |
213.66
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01565 GABA-B receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Muscle relaxant, GABA-B receptor agonist |
|---|
| Comment |
Treatment of fragile X syndrome and autism
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01565 GABA-B receptor agonist
DG01354 Arbaclofen
D09791 Arbaclofen
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Metabotropic glutamate receptor family
GABA (metabotropic)
GABBR
D09791 Arbaclofen (USAN)
Prodrugs [br08324.html]
D09791
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01565 GABA-B receptor agonist
DG01354 Arbaclofen
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 14
1 C8y C 25.6900 -19.0400
2 C1c C 25.6900 -17.6400
3 C8x C 24.5000 -19.7400
4 C8x C 26.8800 -19.7400
5 C1b C 24.5000 -16.9400
6 C1b C 26.8800 -16.9400
7 C8x C 24.5000 -21.1400
8 C8x C 26.8800 -21.1400
9 C6a C 23.3100 -17.6400
10 N1a N 28.1400 -17.6400
11 C8y C 25.6900 -21.8400
12 O6a O 22.0500 -16.9400
13 O6a O 23.3100 -19.0400
14 X Cl 25.6900 -23.2400
BOND 14
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 1 #Up
6 3 7 2
7 4 8 1
8 5 9 1
9 6 10 1
10 7 11 1
11 9 12 1
12 9 13 2
13 11 14 1
14 8 11 2
|
|---|
