KEGG   DRUG: Tirzepatide
Entry
D11360                      Drug                                   

Name
Tirzepatide (USAN)
Formula
C225H348N48O68
Exact mass
4810.5249
Mol weight
4813.4514
Sequence
YXEGTFTSDY SIXLDKIAQK AFVQWLIAGG PSSGAPPPS
  Type
Peptide
Class
Antidiabetic agent
 DG01493  GLP-1 receptor agonist
 DG02044  Hypoglycemics
  DG01493  GLP-1 receptor agonist
Efficacy
Antidiabetic, Gastric inhibitory polypeptide receptor agonist, Glucagon-like peptide 1 (GLP-1) receptor agonist
Comment
Treatment of type 2 diabetes
Target
GIPR [HSA:2696] [KO:K04580]
GLP1R [HSA:2740] [KO:K04581]
  Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP1R
     D11360  Tirzepatide (USAN)
   Gastric inhibitory polypeptide
    GIPR
     D11360  Tirzepatide (USAN)
Other DBs
CAS: 2023788-19-2
PubChem: 384585338
LinkDB

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