KEGG   DRUG: MannitolHelp
Entry
D00062                      Drug                                   

Name
Mannitol (USP);
D-Mannitol (JP17);
Osmitrol (TN);
Tobrex (TN);
Bronchitol (TN)
Product
  Generic
Formula
C6H14O6
Exact mass
182.079
Mol weight
182.1718
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Gastrointestinal agent
 DG01770  Laxative
  DG01767  Osmotic laxative
Remark
Same as: C00392
Therapeutic category: 2190
ATC code: A06AD16 B05BC01 B05CX04 R05CB16
Product: D00062<JP/US>
Product (mixture): D04271<JP/US>
Efficacy
Antihypertensive (intracranial, intraocular), Diagnostic aid (renal function determination), Diuretic
Comment
Osmotic diuretics
Interaction
Drug interaction
Structure map
map07054  Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A06 DRUGS FOR CONSTIPATION
   A06A DRUGS FOR CONSTIPATION
    A06AD Osmotically acting laxatives
     A06AD16 Mannitol
      D00062  Mannitol (USP) <JP/US>
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05B I.V. SOLUTIONS
    B05BC Solutions producing osmotic diuresis
     B05BC01 Mannitol
      D00062  Mannitol (USP) <JP/US>
   B05C IRRIGATING SOLUTIONS
    B05CX Other irrigating solutions
     B05CX04 Mannitol
      D00062  Mannitol (USP) <JP/US>
 R RESPIRATORY SYSTEM
  R05 COUGH AND COLD PREPARATIONS
   R05C EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
    R05CB Mucolytics
     R05CB16 Mannitol
      D00062  Mannitol (USP) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D00062  Mannitol (USP); D-Mannitol (JP17)
Pharmaceutical additives in Japan [BR:br08316]
 Stabilizing agent
  D00062  [009007] D-Mannitol
 Solubilizing agent
  D00062  [009007] D-Mannitol
 Sweetening agent
  D00062  [009007] D-Mannitol
 Base
  D00062  [009007] D-Mannitol
 Flavoring substance
  D00062  [009007] D-Mannitol
 Bonding agent
  D00062  [009007] D-Mannitol
 Suspending agent
  D00062  [009007] D-Mannitol
 Coating agent
  D00062  [009007] D-Mannitol
 Sugarcoated agent
  D00062  [009007] D-Mannitol
 Tonicity agent
  D00062  [009007] D-Mannitol
 Diluting agent
  D00062  [009007] D-Mannitol
 Disintegrant
  D00062  [009007] D-Mannitol
 Solubilization agent
  D00062  [009007] D-Mannitol
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00062  D-Mannitol
  D00062  D-Mannitol injection
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00062
BRITE hierarchy
Other DBs
CAS: 69-65-8
PubChem: 7847130
ChEBI: 16899
ChEMBL: CHEMBL689
DrugBank: DB00742
PDB-CCD: MTL[PDBj]
LigandBox: D00062
NIKKAJI: J2.369H
LinkDB All DBs
KCF data Show

ATOM        12
            1   O1a O    21.5001  -19.4028
            2   C1b C    22.6912  -18.7022
            3   C1c C    23.9524  -19.4028
            4   C1c C    25.1434  -18.7022
            5   C1c C    26.3345  -19.4028
            6   C1c C    27.5957  -18.7022
            7   C1b C    28.7868  -19.4028
            8   O1a O    29.9779  -18.7022
            9   O1a O    23.9524  -20.8041
            10  O1a O    27.5957  -17.3009
            11  O1a O    25.1434  -17.3009
            12  O1a O    26.3345  -20.8041
BOND        11
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     6   7 1
            7     7   8 1
            8     3   9 1 #Down
            9     6  10 1 #Down
            10    4  11 1 #Up
            11    5  12 1 #Up

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