KEGG   DRUG: Dinoprost
Entry
D00081                      Drug                                   

Name
Dinoprost (JP18/USAN/INN);
Prosmon (TN)
Formula
C20H34O5
Exact mass
354.2406
Mol weight
354.481
Structure
Simcomp
Class
Other
 DG01961  Prostaglandin derivative
  DG01960  Prostaglandin F derivative
 DG02573  Prostanoid derivative
  DG01961  Prostaglandin derivative
   DG01960  Prostaglandin F derivative
Remark
Same as: C00639
Therapeutic category: 2499
ATC code: G02AD01
Chemical structure group: DG00447
Product (DG00447): D00081<JP>
Efficacy
Oxytocic, Prostaglandin F receptor agonist
Comment
Prostaglandin derivative
Target
PTGFR [HSA:5737] [KO:K04262]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07035  Prostaglandins
map07228  Eicosanoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G02 OTHER GYNECOLOGICALS
   G02A UTEROTONICS
    G02AD Prostaglandins
     G02AD01 Dinoprost
      D00081  Dinoprost (JP18/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D00081  Dinoprost (JP18/USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostaglandin
    PTGFR
     D00081  Dinoprost (JP18/USAN/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00081  Dinoprost
Other DBs
CAS: 551-11-1
PubChem: 7847149
ChEBI: 15553
ChEMBL: CHEMBL1903583 CHEMBL815
LigandBox: D00081
NIKKAJI: J9.246K
LinkDB
KCF data

ATOM        25
            1   C1y C    26.2459  -14.3536
            2   C1y C    26.2400  -15.7232
            3   C1y C    24.9454  -13.9393
            4   C1b C    27.6327  -13.1279
            5   C1y C    24.9626  -16.1432
            6   C2b C    27.6270  -16.8801
            7   C1x C    24.1513  -15.0498
            8   O1a O    24.5023  -12.6101
            9   C2b C    28.8066  -13.8184
            10  O1a O    24.5311  -17.4840
            11  C2b C    28.8010  -16.2069
            12  C2b C    30.1531  -13.8184
            13  C1c C    29.9748  -16.8801
            14  C1b C    31.3213  -13.1279
            15  C1b C    31.1489  -16.2069
            16  O1a O    29.9748  -18.2382
            17  C1b C    32.4837  -13.8013
            18  C1b C    32.3227  -16.8801
            19  C1b C    33.6577  -13.1223
            20  C1b C    33.5138  -16.2069
            21  C6a C    34.8258  -13.7897
            22  C1b C    34.6704  -16.8801
            23  O6a O    36.0226  -13.0818
            24  O6a O    34.8373  -15.1706
            25  C1a C    35.8616  -16.2069
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 1 #Down
            8     4   9 1
            9     5  10 1 #Down
            10    6  11 2
            11    9  12 2
            12   11  13 1
            13   12  14 1
            14   13  15 1
            15   13  16 1 #Down
            16   14  17 1
            17   15  18 1
            18   17  19 1
            19   18  20 1
            20   19  21 1
            21   20  22 1
            22   21  23 1
            23   21  24 2
            24   22  25 1
            25    5   7 1

» Japanese version   » Back

KEGG   DRUG: Dinoprost tromethamine
Entry
D01352                      Drug                                   

Name
Dinoprost tromethamine (JAN/USP);
Prostin F2 alpha (TN)
Formula
C20H34O5. C4H11NO3
Exact mass
475.3145
Mol weight
475.616
Structure
Simcomp
Class
Other
 DG01961  Prostaglandin derivative
  DG01960  Prostaglandin F derivative
 DG02573  Prostanoid derivative
  DG01961  Prostaglandin derivative
   DG01960  Prostaglandin F derivative
Remark
Same as: C12786
ATC code: G02AD01
Chemical structure group: DG00447
Product (DG00447): D00081<JP>
Efficacy
Oxytocic, Prostaglandin F receptor agonist
Comment
Prostaglandin derivative
Target
PTGFR [HSA:5737] [KO:K04262]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07035  Prostaglandins
map07228  Eicosanoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G02 OTHER GYNECOLOGICALS
   G02A UTEROTONICS
    G02AD Prostaglandins
     G02AD01 Dinoprost
      D01352  Dinoprost tromethamine (JAN/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostaglandin
    PTGFR
     D01352  Dinoprost tromethamine (JAN/USP)
Other DBs
CAS: 38562-01-5
PubChem: 7848415
ChEBI: 31502
ChEMBL: CHEMBL1200896
DrugBank: DB01160
LigandBox: D01352
NIKKAJI: J299.272H
LinkDB
KCF data

ATOM        33
            1   C1y C    22.1239  -14.5461
            2   C1y C    22.1180  -15.9342
            3   C1y C    20.8058  -14.1261
            4   C1b C    23.5295  -13.3037
            5   C1y C    20.8232  -16.3600
            6   C2b C    23.3137  -16.6166
            7   C1x C    20.0008  -15.2518
            8   O1a O    20.3567  -12.7789
            9   C2b C    24.7195  -14.0037
            10  O1a O    20.3858  -17.7191
            11  C2b C    24.5036  -15.9342
            12  C2b C    26.0842  -14.0037
            13  C1c C    25.6934  -16.6166
            14  C1b C    27.2683  -13.3037
            15  C1b C    26.8834  -15.9342
            16  O1a O    25.6934  -17.9931
            17  C1b C    28.4464  -13.9862
            18  C1b C    28.0731  -16.6166
            19  C1b C    29.6364  -13.2980
            20  C1b C    29.2805  -15.9342
            21  C6a C    30.8204  -13.9746
            22  C1b C    30.4528  -16.6166
            23  O6a O    32.0335  -13.2571
            24  O6a O    30.8320  -15.3743
            25  C1a C    31.6602  -15.9342
            26  C1d C    37.9613  -15.2949
            27  C1b C    36.8182  -14.6358
            28  C1b C    37.9613  -16.6422
            29  C1b C    39.1045  -14.6532
            30  N1a N    37.9322  -13.4692
            31  O1a O    35.6750  -15.2949
            32  O1a O    39.1045  -17.3013
            33  O1a O    40.2652  -15.3123
BOND        32
            1    12  14 1
            2    13  15 1
            3    13  16 1 #Down
            4    14  17 1
            5    15  18 1
            6    17  19 1
            7    18  20 1
            8    19  21 1
            9    20  22 1
            10   21  23 1
            11   21  24 2
            12   22  25 1
            13    5   7 1
            14    1   2 1
            15    1   3 1
            16    1   4 1 #Down
            17    2   5 1
            18    2   6 1 #Up
            19    3   7 1
            20    3   8 1 #Down
            21    4   9 1
            22    5  10 1 #Down
            23    6  11 2
            24    9  12 2
            25   11  13 1
            26   26  27 1
            27   26  28 1
            28   26  29 1
            29   26  30 1
            30   27  31 1
            31   28  32 1
            32   29  33 1

» Japanese version   » Back

DBGET integrated database retrieval system