KEGG   DRUG: SulindacHelp
Entry
D00120                      Drug                                   

Name
Sulindac (JP17/USP/INN);
Clinoril (TN)
Product
  Generic
SULINDAC (A-S Medication Solutions), SULINDAC (A-S Medication Solutions), SULINDAC (Actavis Pharma), SULINDAC (Aidarex Pharmaceuticals LLC), SULINDAC (Bryant Ranch Prepack), SULINDAC (Bryant Ranch Prepack), SULINDAC (Bryant Ranch Prepack), SULINDAC (Carilion Materials Management), SULINDAC (Carilion Materials Management), SUNLINDAC (Direct Rx), SULINDAC (Epic Pharma), SULINDAC (Golden State Medical Supply), SULINDAC (H.J. Harkins Company), SULINDAC (Heritage Pharmaceuticals), SULINDAC (Lake Erie Medical DBA Quality Care Products LLC), SULINDAC (Lake Erie Medical DBA Quality Care Products LLC), SULINDAC (Major Pharmaceuticals), SULINDAC (Mylan Institutional), SULINDAC (Mylan Pharmaceuticals), SULINDAC (PD-Rx Pharmaceuticals), SULINDAC (PuraCap Laboratories LLC dba Blu Pharmaceuticals), SULINDAC (Richmond Pharmaceuticals), SULINDAC (State of Florida DOH Central Pharmacy), SULINDAC (State of Florida DOH Central Pharmacy), SULINDAC (State of Florida DOH Central Pharmacy), SULINDAC (State of Florida DOH Central Pharmacy), SULINDAC (Sun Pharmaceutical Industries)
Formula
C20H17FO3S
Exact mass
356.0882
Mol weight
356.4106
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01906  Antiinflammatory drug, acetic acid derivatives
 DG01504  Nonsteroidal antiinflammatory drug (NSAID)
  DG01906  Antiinflammatory drug, acetic acid derivatives
Remark
Same as: C01531
Therapeutic category: 1149
ATC code: M01AB02
Product: D00120<JP/US>
Efficacy
Analgesic, Anti-inflammatory, COX inhibitor
Comment
Acetic acid derivative
Target
PTGS1 (COX1) [HSA:5742] [KO:K00509]
PTGS2 (COX2) [HSA:5743] [KO:K11987]
  Pathway
hsa00590  Arachidonic acid metabolism
Interaction
Drug interaction
Structure map
map07219  Cyclooxygenase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
   M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
    M01AB Acetic acid derivatives and related substances
     M01AB02 Sulindac
      D00120  Sulindac (JP17/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Analgesics
  Nonsteroidal Anti-inflammatory Drugs
   Sulindac
    D00120  Sulindac (JP17/USP/INN)
 Anti-inflammatory Agents
  Nonsteroidal Anti-inflammatory Drugs
   Sulindac
    D00120  Sulindac (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   114  Antipyretics and analgesics, anti-inflammatory agents
    1149  Others
     D00120  Sulindac (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Prostaglandin synthase
    PTGS1 (COX1)
     D00120  Sulindac (JP17/USP/INN) <JP/US>
    PTGS2 (COX2)
     D00120  Sulindac (JP17/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00120  Sulindac
Drug classes of therapeutic agents [br08360.html]
 Antirheumatic and antigout agents
  D00120
 Anesthetics, analgesics and anti-inflammatory drugs
  D00120
BRITE hierarchy
Other DBs
CAS: 38194-50-2
PubChem: 7847188
ChEBI: 9352
ChEMBL: CHEMBL15770
DrugBank: DB00605
LigandBox: D00120
NIKKAJI: J3.501G
LinkDB All DBs
KCF data Show

ATOM        25
            1   C8y C    21.4726  -14.1927
            2   C8y C    21.4726  -12.8437
            3   C2y C    22.6354  -14.8905
            4   C8x C    20.2632  -14.8905
            5   C2y C    23.8449  -12.8437
            6   C8x C    20.2632  -12.1460
            7   C2y C    23.8449  -14.1927
            8   C2b C    22.6354  -16.2394
            9   C8x C    19.1003  -14.1927
            10  C8y C    19.1003  -12.8437
            11  C1a C    24.9378  -14.9605
            12  C8y C    21.4726  -16.9371
            13  X   F    17.9374  -12.1460
            14  C8x C    21.4726  -18.2860
            15  C8x C    20.3097  -16.2394
            16  C8x C    20.3097  -18.9373
            17  C8x C    19.1468  -16.9371
            18  C8y C    19.1468  -18.2860
            19  S4a S    17.9840  -18.9373
            20  C1a C    16.8210  -18.2395
            21  O3c O    17.9840  -20.4962
            22  C1b C    25.0421  -12.1357
            23  C6a C    26.2621  -12.8232
            24  O6a O    27.4570  -12.1165
            25  O6a O    26.2769  -14.2361
BOND        27
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 2
            8     4   9 2
            9     6  10 2
            10    7  11 1
            11    8  12 1
            12   10  13 1
            13   12  14 2
            14   12  15 1
            15   14  16 1
            16   15  17 2
            17   16  18 2
            18   18  19 1
            19   19  20 1
            20   19  21 2
            21    5   7 2
            22    9  10 1
            23   17  18 1
            24    5  22 1
            25   22  23 1
            26   23  24 1
            27   23  25 2

» Japanese version   » Back

DBGET integrated database retrieval system