Entry |
|
Name |
Tolmetin sodium (JAN/USP); Tolmetin sodium dihydrate; Tolectin (TN) |
Product |
|
Generic |
|
Formula |
C15H14NO3. 2H2O. Na
|
Exact mass |
315.1083
|
Mol weight |
315.30
|
Structure |
|
Simcomp |
|
Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
|
Remark |
Product (DG00747): | D00158<US> |
|
Efficacy |
Anti-inflammatory, COX inhibitor |
Target |
|
Pathway |
|
Interaction |
|
Structure map |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AB Acetic acid derivatives and related substances
M01AB03 Tolmetin
D00158 Tolmetin sodium (JAN/USP) <US>
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA21 Tolmetin
D00158 Tolmetin sodium (JAN/USP) <US>
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Tolmetin
D00158 Tolmetin sodium (JAN/USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG00747 Tolmetin
D00158 Tolmetin sodium
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00158 Tolmetin sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00158 Tolmetin sodium (JAN/USP) <US>
PTGS2 (COX2)
D00158 Tolmetin sodium (JAN/USP) <US>
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG00747 Tolmetin
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Other DBs |
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LinkDB |
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KCF data |
ATOM 22
1 C8y C 21.0700 -19.7400
2 C5a C 19.8100 -19.1800
3 N4y N 22.1200 -18.9000
4 C8x C 21.5600 -21.0700
5 C8y C 18.5500 -19.8100
6 O5a O 19.8100 -17.7800
7 C8y C 23.3100 -19.6700
8 C1a C 22.1200 -17.4300
9 C8x C 22.8900 -21.0700
10 C8x C 17.3600 -19.1100
11 C8x C 18.5500 -21.2100
12 C1b C 24.6400 -19.1100
13 C8x C 16.1700 -19.8100
14 C8x C 17.3600 -21.9100
15 C6a C 25.6900 -19.8100
16 C8y C 16.1700 -21.2100
17 O6a O 27.1600 -19.1800 #-
18 O6a O 25.6900 -21.2100
19 C1a C 14.9800 -21.9100
20 Z Na 29.5400 -19.2500 #+
21 O0 O 31.2200 -21.7000
22 O0 O 31.2200 -21.7000
BOND 20
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 2
6 3 7 1
7 3 8 1
8 4 9 1
9 5 10 1
10 5 11 2
11 7 12 1
12 10 13 2
13 11 14 1
14 12 15 1
15 13 16 1
16 15 17 1
17 15 18 2
18 16 19 1
19 7 9 2
20 14 16 2
BRACKET 1 29.1200 -22.6100 29.1200 -20.6500
1 31.8500 -20.6500 31.8500 -22.6100
1 2
ORIGINAL 1 21
REPEAT 1 22
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