KEGG   DRUG: AcetohexamideHelp
Entry
D00219                      Drug                                   

Name
Acetohexamide (JP17/USP/INN);
Dymelor (TN)
Formula
C15H20N2O4S
Exact mass
324.1144
Mol weight
324.3953
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antidiabetic agent
 DG01790  Sulfonamide hypoglycemic
  DG01734  Sulfonamide type sulfonylurea receptor agonist
 DG01508  Sulfonylurea receptor agonist
 DG02044  Hypoglycemics
  DG01790  Sulfonamide hypoglycemic
   DG01734  Sulfonamide type sulfonylurea receptor agonist
Cardiovascular agent
 DG01534  Carbonic anhydrase inhibitor
Remark
Same as: C06806
Therapeutic category: 3961
ATC code: A10BB31
Product: D00219<JP>
Efficacy
Antidiabetic, Hypoglycemic, Sulfonylurea receptor agonist
Comment
Sulfonylurea
Target
ABCC8 (SUR1) [HSA:6833] [KO:K05032]
  Pathway
hsa02010  ABC transporters
hsa04911  Insulin secretion
hsa04930  Type II diabetes mellitus
Interaction
Drug interaction
Structure map
map07018  Sulfonamide derivatives - hypoglycemic agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BB Sulfonylureas
     A10BB31 Acetohexamide
      D00219  Acetohexamide (JP17/USP/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   396  Antidiabetic agents
    3961  Sulfonylureas
     D00219  Acetohexamide (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC subfamily
    ABCC8 (SUR1)
     D00219  Acetohexamide (JP17/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00219  Acetohexamide
Drug classes of therapeutic agents [br08360.html]
 Antidiabetic agents
  D00219
BRITE hierarchy
Other DBs
CAS: 968-81-0
PubChem: 7847286
ChEBI: 28052
ChEMBL: CHEMBL1589
DrugBank: DB00414
LigandBox: D00219
NIKKAJI: J3.355C
LinkDB All DBs
KCF data Show

ATOM        22
            1   C8x C    21.1400  -10.5000
            2   C8y C    21.1400  -11.9000
            3   C8x C    22.3524  -12.6000
            4   C8x C    23.5649  -11.9000
            5   C8y C    23.5649  -10.5000
            6   C8x C    22.3524   -9.8000
            7   S4a S    24.7960   -9.7890
            8   N1b N    26.0012  -10.4847
            9   C5a C    19.9276  -12.6000
            10  C1a C    18.7321  -11.9096
            11  O5a O    19.9275  -13.9998
            12  C5a C    27.1835   -9.8019
            13  N1b N    28.3775  -10.4912
            14  O5a O    27.1835   -8.4002
            15  C1y C    29.5654   -9.8052
            16  C1x C    30.7565  -10.4929
            17  C1x C    31.9690   -9.7929
            18  C1x C    31.9690   -8.3929
            19  C1x C    30.7779   -7.7052
            20  C1x C    29.5655   -8.4052
            21  O3c O    25.7860   -8.7990
            22  O3c O    23.8061   -8.7990
BOND        23
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     2   9 1
            10    9  10 1
            11    9  11 2
            12    8  12 1
            13   12  13 1
            14   12  14 2
            15   13  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   15  20 1
            22    7  21 2
            23    7  22 2

» Japanese version   » Back

DBGET integrated database retrieval system