| Entry |
|
|---|
| Name |
Cisplatin (JP18/USP/INN);
Platinol (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
PtCl2. 2NH3
|
|---|
| Exact mass |
298.9556
|
|---|
| Mol weight |
300.05
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01679 Platinum compound
Transporter substrate
DG02854 SLC22A2 substrate
|
|---|
| Remark |
| Therapeutic category: | 4291 |
|
|---|
| Efficacy |
Antineoplastic, Cell growth inhibitor |
|---|
| Disease |
|
|---|
| Comment |
platinum compound
DNA alkylator
|
|---|
| Target |
DNA |
|---|
| Metabolism |
Transporter: SLC22A2 [HSA: 6582]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07040 | Antineoplastics - alkylating agents |
|
|---|
| Other map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01X OTHER ANTINEOPLASTIC AGENTS
L01XA Platinum compounds
L01XA01 Cisplatin
D00275 Cisplatin (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Alkylating Agents
Alkylating Agents, Other
Cisplatin
D00275 Cisplatin (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
429 Miscellaneous
4291 Other Antitumors
D00275 Cisplatin (JP18/USP/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01679 Platinum compound
D00275 Cisplatin
Transporter substrate
DG02854 SLC22A2 substrate
D00275 Cisplatin
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00275 Cisplatin
Drug metabolizing enzymes and transporters [br08309.html]
Drug transporters
D00275
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00275
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 5
1 Z Pt 34.5801 -25.8301
2 X Cl 35.9846 -25.8301
3 X Cl 34.5743 -27.2286
4 N0 N 31.9200 -25.8300
5 N0 N 33.8100 -24.0800
BOND 2
1 1 2 1
2 1 3 1
|
|---|
