KEGG   DRUG: CisplatinHelp
Entry
D00275                      Drug                                   

Name
Cisplatin (JP17/USP/INN);
Platinol (TN)
Product
  Generic
Formula
PtCl2. 2NH3
Exact mass
298.9556
Mol weight
300.051
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antineoplastic
 DG01679  Platinum compound
Transporter substrate
 DG02854  SLC22A2 (OCT2) substrate
Remark
Same as: C06911
Therapeutic category: 4291
ATC code: L01XA01
Product: D00275<JP/US>
Efficacy
Antineoplastic, Cell growth inhibitor
  Disease
Testicular tumors [DS:H00023]
Ovarian tumors [DS:H00027]
Bladder cancer [DS:H00022]
Comment
platinum compound
DNA alkylator
Target
DNA
Metabolism
Transporter: SLC22A2 [HSA:6582]
Interaction
Drug interaction
Structure map
map07040  Antineoplastics - alkylating agents
Other map
map01524  Platinum drug resistance
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XA Platinum compounds
     L01XA01 Cisplatin
      D00275  Cisplatin (JP17/USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   429  Miscellaneous
    4291  Other Antitumors
     D00275  Cisplatin (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00275  Cisplatin
Antineoplastics [br08340.html]
 D00275
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and germline mutations
  D00275
BRITE hierarchy
Other DBs
CAS: 15663-27-1
PubChem: 7847341
ChEBI: 27899
DrugBank: DB00515
PDB-CCD: CPT[PDBj]
NIKKAJI: J277.914E
LinkDB All DBs
KCF data Show

ATOM        5
            1   Z   Pt   34.5801  -25.8301
            2   X   Cl   35.9846  -25.8301
            3   X   Cl   34.5743  -27.2286
            4   N0  N    31.9200  -25.8300
            5   N0  N    33.8100  -24.0800
BOND        2
            1     1   2 1
            2     1   3 1

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