Entry |
|
Name |
Isoniazid (JP18/USP/INN); Laniazid (TN) |
Product |
|
Generic |
ISONIAZID (A-S Medication Solutions), ISONIAZID (A-S Medication Solutions), ISONIAZID (American Health Packaging), ISONIAZID (Aphena Pharma Solutions - Tennessee), ISONIAZID (Aphena Pharma Solutions - Tennessee), ISONIAZID (CMP Pharma), ISONIAZID (Chartwell RX), ISONIAZID (Chartwell RX), ISONIAZID (Mylan Institutional), ISONIAZID (PD-Rx Pharmaceuticals), ISONIAZID (Preferred Pharmaceuticals), ISONIAZID (Proficient Rx LP), ISONIAZID (REMEDYREPACK), ISONIAZID (RPK Pharmaceuticals), ISONIAZID (Sandoz), ISONIAZID (Teva Pharmaceuticals USA), ISONIAZID 300 MG (Health Department) |
Formula |
C6H7N3O
|
Exact mass |
137.0589
|
Mol weight |
137.14
|
Structure |
|
Simcomp |
|
Class |
Antibacterial
DG01966 Antitubercular
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
|
Remark |
Therapeutic category: | 6222 |
Product (DG00642): | D00346<JP/US> D02002<JP> |
|
Efficacy |
Antibacterial (tuberculostatic) |
Disease |
|
Comment |
Hydrazide
|
Target |
enoyl-[acyl-carrier-protein] reductase (NADH) [KO: K11611] |
Interaction |
|
Structure map |
map07216 | Catecholamine transferase inhibitors |
|
Other map |
map00983 | Drug metabolism - other enzymes |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J04 ANTIMYCOBACTERIALS
J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
J04AC Hydrazides
J04AC01 Isoniazid
D00346 Isoniazid (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antimycobacterials
Antituberculars
Isoniazid
D00346 Isoniazid (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
622 Tuberculosis preparations
6222 Isoniazids
D00346 Isoniazid (JP18/USP/INN)
Drug groups [BR:br08330]
Antibacterial
DG01966 Antitubercular
DG00642 Isoniazid
D00346 Isoniazid
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
DG00642 Isoniazid
D00346 Isoniazid
Antimicrobials [BR:br08307]
Antibacterials
Other antibacterials
Mycolic acid biosynthesis inhibitor
D00346 Isoniazid (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00346 Isoniazid
D00346 Isoniazid tablets
D00346 Isoniazid injection
Drug groups [BR:br08330]
Antibacterial
DG01966 Antitubercular
DG00642 Isoniazid
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
DG00642 Isoniazid
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Other antibacterials
Mycolic acid biosynthesis inhibitor
DG00642 Isoniazid
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 10
1 C8y C 22.4877 -16.7300
2 C5a C 23.6995 -17.4291
3 C8x C 21.2816 -17.4291
4 C8x C 22.4877 -15.3316
5 N1b N 24.9115 -16.7300
6 O5a O 23.6995 -18.8275
7 C8x C 20.0638 -16.7300
8 C8x C 21.2816 -14.6266
9 N1a N 26.1293 -17.4291
10 N5x N 20.0638 -15.3316
BOND 10
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 2
6 3 7 1
7 4 8 2
8 5 9 1
9 7 10 2
10 8 10 1
|