KEGG   DRUG: Mebendazole
Entry
D00368                      Drug                                   
Name
Mebendazole (JAN/USP/INN);
Vermox (TN)
Product
VERMOX (Janssen Pharmaceuticals)
Formula
C16H13N3O3
Exact mass
295.0957
Mol weight
295.29
Structure
Simcomp
Remark
Therapeutic category: 6429
ATC code: P02CA01
Product: D00368<JP/US>
Efficacy
Anthelmintic
  Disease
Gastrointestinal infection, hookworm [DS:H01092]
Gastrointestinal infection, roundworm [DS:H01090]
Gastrointestinal infection, pinworm [DS:H01091]
Gastrointestinal infection, whipworm [DS:H01046]
Comment
Benzimidazole derivative
Target
tubulin alpha [KO:K07374]
tubulin beta [KO:K07375]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
  P02 ANTHELMINTICS
   P02C ANTINEMATODAL AGENTS
    P02CA Benzimidazole derivatives
     P02CA01 Mebendazole
      D00368  Mebendazole (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Antiparasitics
  Anthelmintics
   Mebendazole
    D00368  Mebendazole (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  64  Parasitics (systemic)
   642  Anthelmintics
    6429  Others
     D00368  Mebendazole (JAN/USP/INN)
Antimicrobials [BR:br08307]
 Antiparasitics
  Antinematodal agents
   Benzimidazole derivatives
    D00368  Mebendazole (JAN/USP/INN) <JP/US>
Other DBs
CAS: 31431-39-7
PubChem: 7847434
ChEBI: 6704
PDB-CCD: V95[PDBj]
LigandBox: D00368
J-GLOBAL: J2.773A
LinkDB
KCF data

ATOM        22
            1   C8y C    19.0400  -16.8000
            2   C8y C    19.0400  -15.3300
            3   C8x C    17.8500  -17.4300
            4   N5x N    20.3700  -17.2200
            5   N4x N    20.3700  -14.9100
            6   C8x C    17.8500  -14.6300
            7   C8y C    16.5900  -16.8000
            8   C8y C    21.2100  -16.0300
            9   C8x C    16.5900  -15.3300
            10  C5a C    15.4000  -17.4300
            11  C8y C    14.2100  -16.7300
            12  O5a O    15.4000  -18.9000
            13  C8x C    13.0200  -17.4300
            14  C8x C    14.2100  -15.3300
            15  C8x C    11.9000  -16.8000
            16  C8x C    13.0200  -14.6300
            17  C8x C    11.9000  -15.3300
            18  N1b N    22.5400  -16.0300
            19  C7a C    23.2500  -17.2366
            20  O7a O    24.6400  -17.2250
            21  O6a O    22.5647  -18.4464
            22  C1a C    25.3479  -18.4279
BOND        24
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     4   8 2
            8     6   9 2
            9     7  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 2
            13   11  14 1
            14   13  15 1
            15   14  16 2
            16   15  17 2
            17    5   8 1
            18    7   9 1
            19   16  17 1
            20    8  18 1
            21   18  19 1
            22   19  20 1
            23   19  21 2
            24   20  22 1

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