Entry |
|
Name |
Vidarabine (USAN); Vidarabine monohydrate; Vira-A (TN) |
Formula |
C10H13N5O4. H2O
|
Exact mass |
285.1073
|
Mol weight |
285.26
|
Structure |

|
Simcomp |
|
Class |
Antiviral
DG01440 Arabinofuranosyl type antiviral
DG02840 Anti-herpesvirus agent
|
Remark |
Product (DG00645): | D06298<JP> |
|
Efficacy |
Antiviral, DNA polymerase inhibitor |
Comment |
Arabinofuranosyl derivative
|
Target |
Herpesvirus DNA polymerase [KO: K18964] |
Pathway |
|
Interaction |
|
Structure map |
map07041 | Antineoplastics - antimetabolic agents |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB03 Vidarabine
D00406 Vidarabine (USAN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AD Antivirals
S01AD06 Vidarabine
D00406 Vidarabine (USAN)
Drug groups [BR:br08330]
Antiviral
DG01440 Arabinofuranosyl type antiviral
DG00645 Vidarabine
D00406 Vidarabine
DG02840 Anti-herpesvirus agent
DG00645 Vidarabine
D00406 Vidarabine
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00406 Vidarabine (USAN)
Drug groups [BR:br08330]
Antiviral
DG01440 Arabinofuranosyl type antiviral
DG00645 Vidarabine
DG02840 Anti-herpesvirus agent
DG00645 Vidarabine
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
DG00645 Vidarabine
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 20
1 N4y N 24.1094 -17.9097
2 C8y C 25.2448 -18.7424
3 C1y C 22.7875 -18.3466
4 C8x C 24.5461 -16.5881
5 C8y C 26.3744 -17.9214
6 N5x N 25.3787 -20.1283
7 O2x O 21.6521 -17.5197
8 C1y C 22.3450 -19.6799
9 N5x N 25.9493 -16.5881
10 C8y C 27.6496 -18.4979
11 C8x C 26.6540 -20.6990
12 C1y C 20.5107 -18.3466
13 C1y C 20.9473 -19.6799
14 O1a O 23.1719 -20.8096
15 N5x N 27.7894 -19.8897
16 N1a N 28.7910 -17.6769
17 C1b C 19.1773 -17.9097
18 O1a O 20.1263 -20.8096
19 O1a O 18.1408 -18.8532
20 O0 O 30.8800 -19.5252
BOND 21
1 1 2 1
2 3 1 1 #Up
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 2
9 5 10 1
10 6 11 2
11 7 12 1
12 8 13 1
13 8 14 1 #Up
14 10 15 2
15 10 16 1
16 12 17 1 #Up
17 13 18 1 #Down
18 17 19 1
19 5 9 1
20 11 15 1
21 12 13 1
|