KEGG   DRUG: Sulfadiazine, silverHelp
Entry
D00433                      Drug                                   

Name
Sulfadiazine, silver (USP);
Sulfadiazine silver (JP17);
Silvadene (TN)
Product
SILVER SULFADIAZINE (DIRECT RX), SILVER SULFADIAZINE (A-S Medication Solutions), SILVADENE (A-S Medication Solutions), SILVER SULFADIAZINE (A-S Medication Solutions), SILVER SULFADIAZINE (A-S Medication Solutions), SILVER SULFADIAZENE (Actavis Pharma), SILVER SULFADIAZINE (Aidarex Pharmaceuticals LLC), SILVER SULFADIAZINE (Ascend Laboratories), THERMAZENE (COVIDIEN), SILVADENE (Central Texas Community Health Centers), SILVER SULFADIAZINE (DIRECT RX), SSD CREAM (Dr Reddys Laboratories), SILVER SULFADIAZINE (H.J. Harkins Company), SILVADENE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), SSD CREAM (Lake Erie Medical DBA Quality Care Products LLC), SILVER SULFADIAZINE (Lake Erie Medical DBA Quality Care Products LLC), SILVER SULFADIAZINE (Liberty Pharmaceuticals), SILVER SULFADIAZINE (Medsource Pharmaceuticals), SILVER SULFADIAZINE (NuCare Pharmaceuticals), SILVER SULFADIAZINE (NuCare Pharmaceuticals), SILVER SULFADIAZINE (NuCare Pharmaceuticals), SILVADENE (Pfizer Laboratories Div Pfizer), THERMAZENE (Preferred Pharmaceuticals), THERMAZENE (Preferred Pharmaceuticals), SILVER SULFADIAZINE (Proficient Rx LP), SILVER SULFADIAZINE (REMEDYREPACK), SILVER SULFADIAZINE (REMEDYREPACK), SILVER SULFADIAZINE (RPK Pharmaceuticals), THERMAZENE (Rebel Distributors Corp), SILVER SULFADIAZENE (Rebel Distributors Corp), THERMAZENE (The Pharma Network LLC), SILVER SULFADIAZENE (Unit Dose Services), SILVER SULFADIAZINE (Unit Dose Services), SILVER SULFADIAZENE (Unit Dose Services)
  Generic
Formula
C10H9N4O2S. Ag
Exact mass
355.9497
Mol weight
357.1373
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01787  Sulfonamide antibacterial
  DG01785  Intermediate-acting sulfonamide
Remark
Therapeutic category: 2633
ATC code: D06BA01 J01EC02
Chemical structure group: DG00599
Product (DG00599): D00587<JP/US> D00433<JP/US>
Efficacy
Antibacterial (topical), Folic acid biosynthesis inhibitor
Comment
Sulfonamide
Target
dihydropteroate synthase [KO:K00796]
  Pathway
ko00790  Folate biosynthesis
Interaction
Drug interaction
Structure map
map07016  Sulfonamide derivatives - sulfa drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
    D06BA Sulfonamides
     D06BA01 Silver sulfadiazine
      D00433  Sulfadiazine, silver (USP) <JP/US>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01E SULFONAMIDES AND TRIMETHOPRIM
    J01EC Intermediate-acting sulfonamides
     J01EC02 Sulfadiazine
      D00433  Sulfadiazine, silver (USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Sulfonamides
   Sulfadiazine
    D00433  Sulfadiazine, silver (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   263  Suppurative dermatosis agents
    2633  Sulfa drugs for external use
     D00433  Sulfadiazine, silver (USP); Sulfadiazine silver (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00433  Sulfadiazine silver
Antiinfectives [br08350.html]
 Antibacterials
  D00433
BRITE hierarchy
Other DBs
CAS: 22199-08-2
PubChem: 7847499
ChEBI: 9142
ChEMBL: CHEMBL1382627
DrugBank: DB05245
LigandBox: D00433
NIKKAJI: J550.743J
LinkDB All DBs
KCF data Show

ATOM        18
            1   C8y C    24.2684  -17.0689
            2   S4a S    25.4787  -16.3673
            3   C8x C    24.2741  -18.4665
            4   C8x C    23.0638  -16.3673
            5   N1b N    26.6891  -17.0689 #-
            6   O3c O    26.4610  -15.3792
            7   O3c O    24.4788  -15.3792
            8   C8x C    23.0638  -19.1682
            9   C8x C    21.8534  -17.0572
            10  C8y C    27.9052  -16.3673
            11  C8y C    21.8477  -18.4665
            12  N5x N    27.8995  -14.9639
            13  N5x N    29.1097  -17.0689
            14  N1a N    20.6373  -19.1622
            15  C8x C    29.1097  -14.2623
            16  C8x C    30.3200  -16.3732
            17  C8x C    30.3259  -14.9639
            18  Z   Ag   26.6605  -18.9740 #+
BOND        18
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     2   7 2
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    8  11 2
            11   10  12 2
            12   10  13 1
            13   11  14 1
            14   12  15 1
            15   13  16 2
            16   15  17 2
            17    9  11 1
            18   16  17 1

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