KEGG   DRUG: Nitrofurantoin
Entry
D00439                      Drug                                   

Name
Nitrofurantoin (JAN/USP/INN);
Furadantin (TN);
Macrobid (TN)
Product
NITROFURANTION MACROCRYSTALS (Lake Erie Medical DBA Quality Care Products LLC), NITROFURANTION MACROCRYSTALS (Proficient Rx LP), NITROFURANTION MACROCRYSTALS (Proficient Rx LP), NITROFURANTOIN MACROCRYSTALS (DIRECT RX), MACRODANTIN (Almatica Pharma), NITROFURANTOIN MACROCRYSTALS (Alvogen), NITROFURANTOIN MACROCRYSTALS (American Health Packaging), NITROFURANTOIN MACROCRYSTALS (BluePoint Laboratories), NITROFURANTOIN MACROCRYSTALS (PD-Rx Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (PD-Rx Pharmaceuticals), NITROFURANTOIN MONOHYDRATE MACROCRYSTALLINE (Direct_Rx), NITROFURANTOIN MONO (PharmPak), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (RedPharm Drug), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (A-S Medication Solutions), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (A-S Medication Solutions), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (A-S Medication Solutions), MACROBID (Almatica Pharma), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Alvogen), NITROFURANTOIN MONOHYDRATE/MACROCRYSTALLINE (BluePoint Laboratories), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Bryant Ranch Prepack), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Denton Pharma), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (NuCare Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (PD-Rx Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (PD-Rx Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Preferred Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Proficient Rx LP), MACROBID (REMEDYREPACK), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (REMEDYREPACK), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Unit Dose Services)
  Generic
NITROFURANTION (BluePoint Labortories), NITROFURANTION (Bryant Ranch Prepack), NITROFURANTION (DIRECT RX), NITROFURANTION (Denton Pharma), NITROFURANTION (Proficient Rx LP), NITROFURANTION (Sun Pharmaceutical Industries), NITROFURANTOIN (Actavis Pharma), NITROFURANTOIN (Actavis Pharma), NITROFURANTOIN (American Health Packaging), NITROFURANTOIN (Amneal Pharmaceuticals LLC), NITROFURANTOIN (BluePoint Laboratories), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Lupin Pharmaceuticals), NITROFURANTOIN (Nostrum Laboratories), NITROFURANTOIN (Novel Laboratories), NITROFURANTOIN (NuCare Pharmaceuticals), NITROFURANTOIN (Proficient Rx LP), NITROFURANTOIN (Proficient Rx LP), NITROFURANTOIN (Trigen Laboratories), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (American Health Packaging), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Bryant Ranch Prepack), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Denton Pharma), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Eon Labs), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Northstar RxLLC), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (NuCare Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (NuCare Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (NuCare Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Preferred Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Proficient Rx LP), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Quality Care Products), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (REMEDYREPACK), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (St. Mary's Medical Park Pharmacy), NITROFURANTOIN MACROCRYSTALS (Amneal Pharmaceuticals of New York LLC), NITROFURANTOIN MACROCRYSTALS (AvPAK), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN MACROCRYSTALS (Cadila Healthcare Limited), NITROFURANTOIN MACROCRYSTALS (Denton Pharma), NITROFURANTOIN MACROCRYSTALS (Major Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Novel Laboratories), NITROFURANTOIN MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Proficient Rx LP), NITROFURANTOIN MACROCRYSTALS (REMEDYREPACK), NITROFURANTOIN MACROCRYSTALS (Zydus Pharmaceuticals (USA)), NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (Mylan Pharmaceuticals), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (Amneal Pharmaceuticals LLC), NITROFURANTOIN (AvKARE), NITROFURANTOIN (AvPAK), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Denton Pharma), NITROFURANTOIN (NuCare Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTOIN (Preferred Pharmaceuticals), NITROFURANTOIN (Quality Care Products), NITROFURANTOIN (RedPharm Drug), NITROFURANTOIN (St. Mary's Medical Park Pharmacy)
Formula
C8H6N4O5
Exact mass
238.0338
Mol weight
238.157
Structure
Simcomp
Class
Antibacterial
 DG01552  Hydantoin type nitrofuran
Remark
Same as: C07268
ATC code: J01XE01
Product: D00439<US>
Efficacy
Antibacterial
  Disease
Uncomplicated urinary tract infection [DS:H01176]
Interaction
Other map
map04976  Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XE Nitrofuran derivatives
     J01XE01 Nitrofurantoin
      D00439  Nitrofurantoin (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Nitrofurantoin
    D00439  Nitrofurantoin (JAN/USP/INN)
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D00439
Other DBs
CAS: 67-20-9
PubChem: 7847505
ChEBI: 71415
ChEMBL: CHEMBL572
DrugBank: DB00698
LigandBox: D00439
NIKKAJI: J1.410I
LinkDB
KCF data

ATOM        17
            1   N1x N    23.7300  -16.2400
            2   C5x C    23.3100  -14.9800
            3   C1x C    21.9800  -14.9800
            4   N1y N    21.5600  -16.2400
            5   C5x C    22.6100  -17.0800
            6   O5x O    22.6100  -18.4800
            7   O5x O    24.0800  -13.8600
            8   N2b N    20.3700  -16.9400
            9   C2b C    19.1800  -16.2400
            10  C8y C    17.9900  -16.9400
            11  O2x O    16.8700  -16.1000
            12  C8y C    15.7500  -16.9400
            13  C8x C    16.1700  -18.2700
            14  C8x C    17.5700  -18.2700
            15  N2b N    14.6300  -16.2400 #+
            16  O3a O    13.1600  -17.2200 #-
            17  O3a O    14.6300  -14.9100
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     5   6 2
            7     2   7 2
            8     8   9 2
            9     8   4 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15   10  14 2
            16   12  15 1
            17   15  16 1
            18   15  17 2

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