| Entry |
|
|---|
| Name |
Suprofen (JAN/USP/INN);
Profenal (TN) |
|---|
| Formula |
C14H12O3S
|
|---|
| Exact mass |
260.0507
|
|---|
| Mol weight |
260.31
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivative
Dermatological agent
DG03243 Atopic dermatitis agent
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory |
|---|
| Comment |
Propionic acid derivative
|
|---|
| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AE Propionic acid derivatives
M01AE07 Suprofen
D00452 Suprofen (JAN/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivative
D00452 Suprofen
Dermatological agent
DG03243 Atopic dermatitis agent
D00452 Suprofen
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
D00452 Suprofen
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00452
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 18
1 C8y C 28.3224 -25.4481
2 C5a C 27.1306 -26.1491
3 C8x C 28.3224 -24.0460
4 C8x C 29.5142 -26.1491
5 C8y C 25.9388 -25.4481
6 O5a O 27.1306 -27.5512
7 C8x C 29.5142 -23.4151
8 C8x C 30.7059 -25.5182
9 C8x C 25.4481 -24.1161
10 S2x S 24.7471 -26.2894
11 C8y C 30.7761 -24.0460
12 C8x C 24.0460 -24.0460
13 C8x C 23.6254 -25.4481
14 C1c C 31.9678 -23.4151
15 C6a C 33.1596 -24.1161
16 C1a C 31.9678 -22.0130
17 O6a O 33.1596 -25.5182
18 O6a O 34.3514 -23.4151
BOND 19
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 2
6 3 7 1
7 4 8 2
8 5 9 2
9 5 10 1
10 7 11 2
11 9 12 1
12 10 13 1
13 11 14 1
14 14 15 1
15 14 16 1
16 15 17 2
17 15 18 1
18 8 11 1
19 12 13 2
|
|---|
