KEGG   DRUG: ProbenecidHelp
Entry
D00475                      Drug                                   

Name
Probenecid (JP17/USP/INN);
Benemid (TN)
Product
  Generic
Formula
C13H19NO4S
Exact mass
285.1035
Mol weight
285.3593
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG02042  Uricosurics
Enzyme inhibitor
 DG01643  CYP2C9 inhibitor
 DG01933  CYP2C19 inhibitor
Transporter inhibitor
 DG02867  ABCC2 (MRP2) inhibitor
 DG02883  SLC22A7 (OAT2) inhibitor
 DG02866  SLC22A8 (OAT3) inhibitor
Remark
Same as: C07372
Therapeutic category: 3942
ATC code: M04AB01
Product: D00475<JP/US>
Efficacy
Gout suppressant, Uricosuric
  Disease
Gout and gouty arthritis [DS:H01532]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M04 ANTIGOUT PREPARATIONS
   M04A ANTIGOUT PREPARATIONS
    M04AB Preparations increasing uric acid excretion
     M04AB01 Probenecid
      D00475  Probenecid (JP17/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Antigout Agents
  Probenecid
   D00475  Probenecid (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   394  Gout preparations
    3942  Probenecids
     D00475  Probenecid (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00475  Probenecid
  D00475  Probenecid tablets
Drug classes of therapeutic agents [br08360.html]
 Antirheumatic and antigout agents
  D00475
BRITE hierarchy
Other DBs
CAS: 57-66-9
PubChem: 7847541
ChEBI: 8426
ChEMBL: CHEMBL897
DrugBank: DB01032
LigandBox: D00475
NIKKAJI: J1.382J
LinkDB All DBs
KCF data Show

ATOM        19
            1   C8y C    23.5954  -17.3956
            2   S4a S    22.3946  -16.6962
            3   C8x C    23.5954  -18.7944
            4   C8x C    24.8135  -16.6962
            5   N1c N    21.1824  -17.3897
            6   O3c O    21.3922  -15.6995
            7   O3c O    23.3797  -15.6995
            8   C8x C    24.8135  -19.4996
            9   C8x C    26.0257  -17.3956
            10  C1b C    19.9702  -16.6904
            11  C1b C    21.1824  -18.7827
            12  C8y C    26.0257  -18.7944
            13  C1b C    18.7578  -17.3782
            14  C1b C    19.9702  -19.4762
            15  C6a C    27.2439  -19.4996
            16  C1a C    17.5456  -16.6845
            17  C1a C    19.9702  -20.8750
            18  O6a O    27.2439  -20.8984
            19  O6a O    28.4561  -18.7944
BOND        19
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     2   7 2
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    5  11 1
            11    8  12 2
            12   10  13 1
            13   11  14 1
            14   12  15 1
            15   13  16 1
            16   14  17 1
            17   15  18 1
            18   15  19 2
            19    9  12 1

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